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Elucidating the glioblastoma epigenome


Project Description

A graduate with interest in Brain Tumourigenesis and with experience in Molecular Biology or Cell Biology with at least an upper second class honours degree is required for this project based in the Brain Tumour Research Centre of Excellence led by Prof Silvia Marino at the Blizard Institute. The group is a multidisciplinary research group composed of basic scientists, computational biologists and clinical researchers focusing on the integration and analysis of large-scale (epi)genetic and (epi)genomic data as well as on focussed target gene approach studies to understand the role of dysregulated epigenetic mechanisms in initiation and progression of brain tumours (Badodi et al. Cell Reports 2017, Niklison-Chirou et al. G&D 2017, Dibenedetto et al. Stem Cell Reports 2017).

For more information about the lab please visit https://www.qmul.ac.uk/blizard/staff/centre-for-genomics-and-child-health/staff/silvia-marino.html

The program of work is a collaboration with the groups of Prof Denise Sheer also at the Blizard and other national and international research groups. The research project will use molecular biology, cellular biology, next generation sequencing, genetics, epigenetics and biochemical methods. All applicants should have a strong motivation for pursuing an ambitious research agenda in an international and competitive research environment.

The post is based in the Blizard Institute, Whitechapel Campus. The Blizard Institute provides a stimulating scientific environment and state of the art infrastructure and facilities. In the 2014 REF, Queen Mary University of London (QMUL) is ranked 11th out of total institutions and 9th out of multi-faculty universities. The Medical School is 7th in Clinical Medicine and 5th in Public Health, Health Services and Primary Care with 90% of research rated as 3*+ 4* in the overall power ranking for these unit of assessments. In Clinical Medicine, QMUL was ranked 4th nationally for quality of outputs.

Funding Notes

This 3-years studentship is funded by Brain Tumour Research charity and comes with a tax-free stipend at MRC-rate (£17,009 pa). Home/EU tuition fees will be paid by the funding body. All students must meet English language entry requirements. Interviews will take place the week commencing 24 February 2020. The studentship is available immediately and candidates should be available to start in April 2020 or shortly thereafter.

How good is research at Queen Mary University of London in Clinical Medicine?

FTE Category A staff submitted: 144.11

Research output data provided by the Research Excellence Framework (REF)

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