Attend the Virtual Global Study Fair | Register Now Attend the Virtual Global Study Fair | Register Now

Elucidating the pathobiology of Candida albicans

   School of Biosciences

This project is no longer listed on and may not be available.

Click here to search for PhD studentship opportunities
  Dr Becky Hall  Applications accepted all year round  Funded PhD Project (UK Students Only)

About the Project

The Hall lab is interested in understanding the biology and virulence factors of fungal pathogens. Our research largely focuses on the opportunistic fungal pathogen Candida albicans, which causes a range of infections from superficial mucosal infections (i.e. thrush) to life-threatening systemic disease (i.e. candidiasis).

During colonisation of the human host, C. albicans has to respond and adapt to a wide range of environmental factors, which regulate key virulence factors of the pathogen. In addition to host derived environmental signals, C. albicans also responds to communication molecules produced from the microbiota and directly interacts with other commensal and pathogenic microbes. In order to understand how all these factors affect the pathobiology of C. albicans we are interested in several projects including:

· Investigating how adaptation to the host environment affects the structure of the fungal cell wall, and the impact this has on the host-pathogen interaction.

· Elucidating the role of direct cell-cell interactions of C. albicans with the microbiome

· Deciphering the role of polymicrobial interactions in regulating antimicrobial susceptibility

· Exploring the impact of microbial communication molecules on the human host

In order to achieve our research goals, we use cutting-edge techniques in transcriptomics, live cell imaging, molecular biology, cell biology, microbiology, immunology and biochemistry. For more details about our research, please contact Dr Rebecca Hall and visit our website. You will work in the dynamic environment of the School of Biosciences, based in the Division of Natural Sciences at the University of Kent. The School is home to the Kent Fungal Group, formed of 9 independent research groups, focussing on various aspects of fungal biology and microbiology with whom we work closely with and collaborate with.

If you are an enthusiastic individual interested in starting a PhD then we would be delighted to hear from you. A background in biological sciences (i.e. microbiology, molecular biology, immunology) would be advantageous, and due to the competitive nature of the studentships, an upper class degree (2:1 or above) together with demonstrable research experience is highly desirable.


This is a self-funded PhD open to all applicants. Fees for the 2022 academic year are £4,596 for home students, £21,200 for European students and overseas students. Additional bench fees depend on the aims of the project and will be discussed during interview.

How to apply


Contact: for further information or informal enquiries, please contact Dr Rebecca Hall

You will need to apply through the online application form on the main University website. Please note that you will be expected to provide personal details, education and employment history and supporting documentation (Curriculum Vitae, transcript of results, two academic references). Please apply here.


Kumwenda P., et. al. (2022) Oestrogen promotes innate immune evasion of Candida albicans through inactivation of complement. Cell Reports 38(1):110183
Alam, F., et al (2019) Candida albicans enhances the resistance of Pseudomonas aeruginosa to meropenem is a polymicrobial biofilm. Journal of Antimicrobial Chemotherapy, dkz514.
Cottier F., et. al. (2019) Remasking of Candida albicans b-glucan in response to environmental pH is regulated by quorum sensing mBio, e02347-19.
Kousser C., et. al. (2019) Pseudomonas aeruginosa inhibits Rhizopus microsporus germination through sequestration of free environmental iron. Scientific reports, 9. 5714.
Sherrington S. et al. (2017) Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition. PLoS Pathog 13(5): e1006403

How good is research at University of Kent in Biological Sciences?

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities
Search Suggestions
Search suggestions

Based on your current searches we recommend the following search filters.

PhD saved successfully
View saved PhDs