Imperial College London Featured PhD Programmes
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EMBLA project - RNA Computational Biology and comparative genomics

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

PhD position is available for a highly motivated trainee in the field of Computational Biology/ Bioinformatics at Neurotranscriptomics Laboratory within the Garvan Institute of Medical Research in Sydney.

Our research focuses on understanding how phenotypic complexity can arise during evolution (Gueroussov et al. 2017 Cell, Avgan et al. 2019 Genome Biology, Sterne-Weiler et al. Mol Cell. 2018). Our work focuses on the role of alternative splicing, and other post-transcriptional mechanisms, in expanding gene and protein function (Quesnel-Vallières et al. 2019. Nature Review Genetics). We are a multi-disciplinary lab and candidates will have opportunities to learn both wet and dry skills (depending on interest and experience). For details see https://weatheritt2.github.io and http://www.emblaustralia.org/about/our-people/robert-weatheritt

Requirements for Computational Biology students:
The candidate should have experience in computational biology or bioinformatics. We are particularly interested in a candidate with a biological background. Expertise in analyzing RNA-seq, nanopore, scRNA-seq, CLiP-seq or ATAC-seq would be a bonus. International candidates with publication/s and/or a Master’s degree with distinction are encouraged to apply.

If you are interested, please send your c.v. and a cover letter explaining your interest to: .

This EMBL Australia affiliated project offers the opportunity to do great science in one of the best genomics and transcriptomics biomedical centres in the world, and to combine that with a great lifestyle in one of the best cities in the world.

Funding Notes

All PhD students at the Garvan Institute must have a scholarship from The University of New South Wales or through another government, trust or philanthropic organisation. Before applying for a scholarship, you must have agreed on a project with an institute supervisor. For international students, an English proficiency test is required (except students from the UK, USA, Canada). Our laboratory is committed to diversity and equality.

References

Avgan N, Wang JI, Fernandez-Chamorro J, Weatheritt RJ. (2019). Multilayered control of exon acquisition permits the emergence of novel forms of regulatory control. Genome Biology Jul 17;20(1):141.
Gueroussov, S, et al. (2017), ‘Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing.’, Cell, 170 (2), 324-339.e23.
Sterne-Weiler et al. (2018) Efficient and Accurate Quantitative Profiling of Alternative Splicing Patterns of Any Complexity on a Laptop. Molecular Cell. 2018 Oct 4;72(1):187-200.e6
Quesnel-Vallières M, et al.. Autism spectrum disorder: insights into convergent mechanisms from transcriptomics. Nature Review Genetics. 2019 Jan 20(1):51-63

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