Post-transcriptional mechanisms greatly diversify transcriptomes and proteomes and play critical roles in fundamental biological processes associated with normal physiology, human diseases and disorders. However, it is inherently stochastic and results in extensive biological noise. In close collaboration with the Garvan-Weizmann Centre for Cellular Genomics, this project will investigate mechanisms underlying genetic variation in the transcriptome using single-cell data. This project is suited for students with some experience in computational biology.
This EMBL Australia affiliated project offers the opportunity to do great science in one of the best genomics and transcriptomics biomedical centres in the world, and to combine that with a great lifestyle in one of the best cities in the world.