About the Project
We are looking for a highly motivated PhD candidate willing to work at the interface between chemistry, biology and computational sciences. Ideally, the candidate should have a degree in chemistry, or a related discipline. Experience in the synthesis and characterization of polymers is highly desired.
This project is highly multidisciplinary and involves a collaboration between Dr Paco Fernandez-Trillo (School of Chemistry) and Dr Sara Jabbari (School of Mathematics). The PhD candidate will work alongside another PhD student working in the development of computational models. Both PhD candidates will be trained in Microbiology and join a vibrant research team of chemists, pharmacists, biochemists and microbiologists.
For further details about the project, please contact Dr Fernandez-Trillo ([Email Address Removed]) or Sara Jabbari ([Email Address Removed]).
Please contact [Email Address Removed] for details regarding funding and the application procedure.
2. Lui, L. T. et al. Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes. Nature Chemistry 5, 1058–1065 (2013).
3. Perez-Soto, N. et al. Engineering microbial physiology with synthetic polymers: cationic polymers induce biofilm formation in Vibrio cholerae and downregulate the expression of virulence genes. Chem Sci 8, 5291–5298 (2017).
4. Perez-Soto, N., Creese, O., Fernandez-Trillo, F. & Krachler, A.-M. Aggregation of Vibrio cholerae by Cationic Polymers Enhances Quorum Sensing but Overrides Biofilm Dissipation in Response to Autoinduction. ACS Chemical Biology 13, 3021–3029 (2018).
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