About the Project
In this PhD project you will aim to exploit membrane enzymes for applications in bioelectrocatalysis, in particular for bioenergy related applications such as biofuel cells. Your aim is supported by our recent results, which show that ‘cheap-to-produce’ crude membrane extracts are suitable catalyst systems and that amphiphilic polymers are able to induce an unprecedented improvement in biocatalyst stability. As a proof-of-principle, your will use two membrane enzymes, membrane-bound hydrogenase (hydrogen oxidation) and cytochrome bo3 (oxygen reduction), to create a cheap and robust enzyme-based hydrogen-air fuel cell. This technology will advance the area of industrial biomanufacturing and open up the use of membrane enzymes in biocatalysis and in particularly, bioelectrocatalysis.
Khan, S., Li, M., Muench, S.P., Jeuken, L.J.C., Beales, P. A. (2016) Durable Proteo-Hybrid Vesicles for the Extended Functional Lifetime of Membrane Proteins in Bionanotechnology Chem. Commun., 52, 11020-11023.DOI: 10.1039/C6CC04207D
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