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Enjoyable interventions to improve inflammatory status, glycaemic control and energy balance – metabolic and affective responses to body temperature elevations


Project Description

The aim of this PhD project is to assess the use of increasing body temperature to benefit health - the overarching aim is to inform health interventions based on thermal therapy. Body temperature will be manipulated using techniques such as passive hot water immersion or exposure to hot environments, and different temperature ranges and heat-exposed body surface areas will be investigated. Local cooling will be employed with the aim to increase intervention acceptability and overall enjoyment. The potential to induce blood borne markers positively affecting inflammatory disease (e.g. Type II Diabetes, Cardiovascular Disease) and the potential to improve glycaemic control and energy balance will be assessed, as well as the subjective enjoyment of these interventions.

The assessment of physiological and subjective measures in tandem are an integral part of these studies: this research does not only investigate the potential physiological benefits, but also evaluates subjective responses to heat, which may affect compliance to thermal interventions.

Experimental evidence will be gained through a range of techniques, including biochemical analysis (plasma markers determined using ELISA-based methods, intracellular markers by flow cytometry), exercise and environmental physiology (determination of temperature of various bodily sites, control of environmental temperature, assessment of energy expenditure, glucose tolerance testing), and perceptions (subjective enjoyment/strain).

All applications are made online, please select the school/department name under the programme name section and include the quote reference number.

https://www.lboro.ac.uk/study/postgraduate/apply/research-applications/

Entry Requirements

A relevant Master's degree and / or experience in one or more of the following will be an advantage:
- MSc in Exercise Physiology, Sport and Exercise Nutrition
- Experience in laboratory testing
- Experience in any of the techniques mentioned in the project description

Funding Notes

This is an open call for candidates who are sponsored or who have their own funding. If you do not have funding, you may still apply, however Institutional funding is not guaranteed. Outstanding candidates (UK/EU/International) without funding will be considered for funding opportunities which may become available in the School.

UK/EU Fee band: Research Band 2 Laboratory Based (£4,195)
International Fee band: Research Band 2 Laboratory Based (£20,500)

References

Freely accessible research papers:
https://kids.frontiersin.org/article/10.3389/frym.2019.00098
https://www.ncbi.nlm.nih.gov/pubmed/30756293
https://www.ncbi.nlm.nih.gov/pubmed/28944271

Podcast:
https://jappl.podbean.com/e/the-acute-and-chronic-effects-of-hot-water-immersion-on-inflammation-and-metabolism-in-sedentary-overweight-adults/

Podcast-related publication:
https://www.ncbi.nlm.nih.gov/pubmed/30335579

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