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Epigenetic dysregulation in glioblastoma

   Blizard Institute

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  Prof S Marino, Dr L Stojic  No more applications being accepted  Funded PhD Project (UK Students Only)

About the Project

We are seeking a graduate with interest in Brain Tumourigenesis and with experience in Molecular Biology or Cell Biology or Computer Science with at least an upper second class honours degree to join the Brain Tumour Research Centre of Excellence led by Prof Silvia Marino at the Blizard Institute. The group is a multidisciplinary research group composed of basic scientists, computational biologists and clinical researchers focusing on the integration and analysis of large-scale (epi)genetic and (epi)genomic data as well as on focussed target gene approach studies to understand the role of dysregulated epigenetic mechanisms in initiation and progression of brain tumours (Badodi et al. Nat. Commun. 2021, Freire-Benéitez et al NAR Cancer 2021, Badodi et al. Cell Reports 2017, Niklison-Chirou et al. G&D 2017). For more information about the lab please visit

The project will focus on the mechanistic characterisation of tumour defining epigenetic changes in glioblastoma subgroups and will study how they can inform precision targeting of these neoplasms. We will use molecular biology, cellular biology, next generation sequencing, genetics, epigenetics and biochemical methods. The possibility of being involved and contributing to the computational analysis of next generation sequencing datasets will be available. All applicants should have a strong motivation for pursuing an ambitious research agenda in an international and competitive research environment.

The post is based in the Blizard Institute, Whitechapel campus. The Blizard Institute provides a stimulating scientific environment and state of the art infrastructure and facilities. In the 2014 REF, Queen Mary University of London (QMUL) is ranked 11th out of total institutions and 9th out of multi-faculty universities. The Medical School is 7th in Clinical Medicine and 5th in Public Health, Health Services and Primary Care with 90% of research rated as 3* + 4* in the overall power ranking for these unit of assessments. 

Interviews will take place shortly after the deadline for submission of applications. The studentship will start in September 2022.

Please apply using this link:

Funding Notes

This is a 4-year studentship, funded by Brain Tumour Research charity and comes with a tax-free stipend at MRC-rate (£18,062 pa).
UK student tuition fees will be paid by the funding body (for EU students, please read fee guidance here:
Additional funding for travel, conference attendance and consumables is available.
International students are required to provide evidence of their proficiency in English language skills.


Badodi et al. Nat. Commun. 2021, Freire-Benéitez et al NAR Cancer 2021, Badodi et al. Cell Reports 2017, Niklison-Chirou et al. G&D 2017

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