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(EPSRC DTP) Understanding the impact of capillary network structure on oxygen delivery in the brain using MRI and computational modelling

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  • Full or part time
    Dr L Parkes
    Dr A Revell
    Dr H Boutin
    Prof Stuart Allan
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Funding Notes

EPSRC DTP studentship with funding for a duration of 3.5 years to commence in September 2020. The studentship covers UK/EU tuition fees and an annual minimum stipend £15,285 per annum. Due to funding restrictions, the studentship is open to UK and EU nationals with 3 years residency in the UK.

As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

References

Wardlaw J et. al, ‘Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration’ Lancet Neurol 2013; 12: 822–38.

H. Robson, K. Specht, H. Beaumont, L. Parkes, K. Sage, M.A. Lambon Ralph & R. Zahn, ‘Beyond the Lesion: Arterial Spin Labelling Shows Functional Depression of Intact Neural Tissue in Chronic Aphasia. Cortex [2017]

Østergaard, L., et al., Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. Journal of Cerebral Blood Flow & Metabolism, 2015. 36(2): p. 302-325.

Al-Bachari S, Vidyasagar R, Emsley HCA, Parkes LM, ’Structural and Physiological Neurovascular Changes in Idiopathic Parkinson’s Disease and its Clinical Phenotypes’ Journal of Cerebral Blood Flow and Metabolism, 37(10) 3409–3421 [2017]

Jespersen, S.N. and L. Ostergaard, The roles of cerebral blood flow, capillary transit time heterogeneity, and oxygen tension in brain oxygenation and metabolism. J Cereb Blood Flow Metab, 2012. 32(2): p. 264-77.



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