About the Project
Cellular signal transduction pathways are key regulators of learning in the healthy brain and are frequently mis-regulated in neurodegenerative disorders. Based on previous results and published evidence we hypothesise that disease progression involves the loss of neuroprotective mechanisms and that neuroprotection can be provided by the MAPK (mitogen-activated protein kinase) ERK5. In this project, you will therefore investigate the role of the ERK5 MAPK pathway in the brain using a number of innovative technologies, including biological model systems, biochemistry, molecular biology, modern imaging systems as well as proteomic technologies. This programme of work aims to establish ERK5 as a novel target for the treatment of Alzheimer’s disease and other neurodegenerative disorders.
The research will take place at the School of Pharmacy and Medical Sciences, University of Bradford; a highly active research environment with an excellent track record in PhD training and completion. You will also be supported by an active, ongoing education program of seminars and student-led events.
Based on your current searches we recommend the following search filters.
Based on your current search criteria we thought you might be interested in these.