Dr Lucy O'Malley, Dr Philip Riley, Prof A-M Glenny
Applications accepted all year round
Self-Funded PhD Students Only
About the Project
Oral mucositis is characterised by painful ulcers of the mouth and is a side effect of some cancer treatments. Typically, it can affect over 75% of high risk patients (Scully, 2006) causing severe pain and difficulty with eating and drinking that may necessitate pain relief treatment and nasogastric or intravenous feeding. Mucositis is therefore a condition which can have substantial impact on quality of life and further compounds the suffering cancer patients. At present, there is no known standard of care for the prevention of oral mucositis. It is therefore important to establish the evidence base around how best to prevent patients undergoing cancer treatment from developing mucositis. A programme of work is ongoing to develop this evidence base and this PhD project would contribute to this.
The methodological focus of this project is on evidence synthesis and the student would become experienced in systematic review methods. Additionally there will be scope for the developing the project to incorporate mixed methods including qualitative work around the implementation of evidence.
Applicants are expected to hold, or about to obtain, a minimum upper second class undergraduate degree (or equivalent) in Biological or Medical Sciences, Psychology or other relevant scientific/numerate discipline. A Masters degree in a relevant subject or experience in Public Health, Health Sciences of related area is desirable. Candidates with interests in evidence based healthcare, evidence synthesis or guideline development are encouraged to apply.
For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website (https://www.bmh.manchester.ac.uk/study/research/apply/). Informal enquiries may be made directly to the primary supervisor. On the online application form select PhD Dental Health Sciences.
For international students we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences. For more information please visit www.internationalphd.manchester.ac.uk
Funding Notes
Applications are invited from self-funded students. This project has a Band 1 fee. Details of our different fee bands can be found on our website (https://www.bmh.manchester.ac.uk/study/research/fees/). For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website (https://www.bmh.manchester.ac.uk/study/research/apply/).
As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit
References
Riley P, Glenny AM, Worthington HV, Littlewood A, Clarkson JE, McCabe MG. Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy. Cochrane Database of Systematic Reviews 2015, Issue 12. Art. No.: CD011552. DOI: 10.1002/14651858.CD011552.pub2.
Riley P, Glenny AM, Worthington HV, Littlewood A, Fernandez Mauleffinch LM, Clarkson JE, McCabe MG. Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors. Cochrane Database of Systematic Reviews 2017, Issue 11. Art. No.: CD011990. DOI: 10.1002/14651858.CD011990.pub2.
Scully C, Sonis S, Diz PD. Oral mucositis. Oral Diseases 2006;12(3):229‐41.
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