About the Project
We will use our knowledge of protein structure and sequence data from clinical isolates to identify constraints on the evolution of AMR. We will use phylogenetic methods to reconstruct evolutionary pathways, and determine how these are constrained by protein structure and function. We will use novel methods to identify coevolution within bacteria as they gain resistance. The ultimate aim is to identify signals that resistance is about to emerge, and therapies that can prevent it.
Training/techniques to be provided:
Training will be provided in protein structure analysis, programming and evolutionary biology.
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or equivalent) in biology, biochemistry or a related subject.
For international students we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences. For more information please visit www.internationalphd.manchester.ac.uk
As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
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