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Examining Structure/Function of Cardiac Muscle Cells

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  • Full or part time
    Dr Xin Shen
    Prof W Louch
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

About This PhD Project

Project Description

Applicants are invited to apply for a PhD position based at IEMR, situated in the picturesque Capital of Norway. The position will be 3 years in duration. The student will be supported by an annual salary between NOK 479 600 and NOK 523 200 NOK, funded by Norwegian Regional Health Authority (Helse Sør-Øst). The project will be conducted in the group of Professor William Louch, supervised by Dr. Xin Shen, and aligned to ongoing collaborations within the Jebsen Center for Cardiac Research. The research quality of this laboratory is exemplified by the publishing of articles in world leading journals such as Cardiovascular Research, Circulation Research, JBC, Elife and JACC.

More about the position

Contraction and relaxation of cardiac muscle cells, and thus the whole heart, are critically dependent on dyads. These structures allow efficient control of calcium release into the cytosol, and also its removal. Dyads are formed gradually during development and break down during disease. However, the precise nature of dyadic structure is unclear, as are the triggers and consequences of altering dyadic integrity during diseases such as heart failure.

The present project is aimed at examining these questions, and will employ advanced cellular imaging techniques (super-resolution and electron microscopy), together with experiments focused on cellular and molecular biology. The project has highly qualified national and international collaborators.

The main purpose of the fellowship is to qualify researchers for work in higher academic positions within their disciplines.

Qualification requirements

We are looking for talented and highly motivated candidates of all nationalities who have a keen interest in cellular and cardiovascular research. The applicant is expected to hold, or soon to complete, a Master’s degree (MRes/MSc) in human biology, cell biology or a related field and have a good command of English. Value will be placed on compatibility of the applicant’s professional and personal disposition. Experience with techniques for imaging, cell biology, electrophysiology, molecular biology, viral transduction, or mathematical modeling is considered an asset.

We offer

• A stimulating, challenging and friendly international working environment with broad expertise
• Salary NOK 479 600 – 523 200 per annum, depending on qualifications
• Technical assistance and training
• Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include:
• Cover letter (statement of motivation, summarizing scientific work and research interest)
• CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
• Copies of educational certificates (academic transcripts only)
• A complete list of publications
• List of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered in our electronic recruiting system ( The attachments should be in the form of one or two pdf files that includes all of these requested items.
Foreign applicants are advised to attach an explanation of their University’s grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented, academic qualifications in regards to the project description, and the candidate’s motivation and personal suitability. Interviews with the best qualified candidates will be arranged. It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

About us

Oslo University Hospital is a highly specialized hospital, with extensive regional and local responsibilities. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year, and contribute approximately 50 percent of all medical and health care research conducted at Norwegian hospitals. We are also a significant contributor to the education of a large range of health care personnel.

The Institute for Experimental Medical Research (IEMR) is an innovative and dynamic medical research environment that conducts research focused on understanding the molecular basis of heart failure development. With approximately 70 employees and six research groups, our expertise spans molecular biology, physiology and cardiology. For more about IEMR, please see the institute web site.

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