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Examining the long-term effects of a concussive impact on accumulation of abnormal tau

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Applications are invited to undertake a PhD/Higher Degree by Research (HDR) to investigate how concussive impacts can lead to later neurodegenerative disease. This will use our well-characterised pre-clinical large animal model of concussion with examination on how this promotes aggregation of abnormal tau and the relationship with functional impairment. As such the project will involve a comprehensive behavioural battery, neuroimaging (DTI and rs-fMRI) and immunohistochemical analysis of tau aggregates. Interest in the long-term effects of concussive impacts is growing, with repeated injuries linked to the development of chronic traumatic encephalopathy, although the mechanism driving this assocation is not yet known

This will be under the supervision of Dr Frances Corrigan within the Head Injury laboratory at the University of South Australia.

Students will possess an undergraduate degree with Honours (first class, or anticipation of 1st class Honours in 2017) in Biomedical Science, Health Sciences or equivalent degree. Interested students must be eligible for enrollment in a PhD program at University of South Australia and eligible to apply for an Australian Postgraduate Award or equivalent.

Funding Notes

Although the project is fully funded, students will be required to secure their own funding, with support from the supervisors.

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