This PhD programme aims to develop evidence-based exercise interventions to examine the effects and underlying mechanisms of exercise on cardiometabolic health and inflammation in postmenopausal women receiving adjuvant therapy for breast cancer. Specifically, the PhD aims to:
- Review the effects of obesity, metabolic syndrome, weight gain on cancer endpoints and treatment-related outcomes, the mechanisms for the effects of exercise on cardiometabolic, inflammatory, and treatment-related outcomes in in postmenopausal women receiving adjuvant therapy for breast cancer.
- Investigate the effects of acute bouts of exercise on inflammation and treatment efficacy and tolerance in postmenopausal women receiving adjuvant therapy for breast cancer.
- Understand the trajectory of obesity, weight gain, and related symptoms and biomarkers in postmenopausal women receiving adjuvant therapy for breast cancer.
- Explore whether biomarkers (cardiometabolic, inflammation, immune competency) explain fluctuations in treatment-related outcomes.
- Examine the effects of exercise on cardiometabolic health and inflammation in postmenopausal women receiving adjuvant therapy for breast cancer.
It is anticipated this research will draw on a range of methodologies within exercise physiology, immunology, as well as other aspects of clinical cancer care. The precise research question(s) and methodologies adopted will be negotiated with the successful applicant.
The studentship is for three years and is intended to start in December 2021. The studentship provides a tax-free stipend of £15,609 per year plus the tuition fees at the UK rate. We anticipate submission at month 36 of study. An additional maximum of 12 months can be applied for but the pro-rata cost of £1,000 for this additional period will need to be covered by the applicant, should they wish for this additional time. Due to funding restrictions, this studentship is only open to UK applicants.
- An undergraduate degree (2:1 or above with honours) in Sport & Exercise Science, Biological Sciences, Physiology, Biochemistry, or related area (cv)
- Good IT skills, including data analysis skills (cv)
- Good communication and interpersonal skills, written and oral (cv and interview)
- Knowledge of delivering exercise sessions to clinical populations (cv and interview)
- Good understanding of clinical and quantitative research methods and designs (cv and interview)
- Understanding of the mechanisms that underpin the role of exercise in the prevention and management of chronic diseases (cv and interview)
- Experience of analysing quantitative data (cv and interview)
- Ability to work as part of a multidisciplinary team (cv)
- Ability to work independently and set realistic but attainable goals (cv and interview)
- Commitment to the University’s policy framework on diversity and the University’s and partner hospital’s policies on health and safety (cv and interview)
- The studentship will involve times to suit the scheduling of study participants which will include some evenings, weekends and bank holidays (interview)
- Commitment to open science and improving transparency and a credibility within the field of clinical exercise science (interview)
- A masters-level qualification in Sport & Exercise Science, Biological Sciences, Physiology, Biochemistry, or related area (cv)
- Accreditation or desire to work towards accreditation from relevant professional body e.g., BASES (cv)
- A current first aid or basic support qualifications from a recognised organisation (cv)
- Personal initiative, reliability, attention to detail (cv and interview)
- Evidence of managing research projects (cv and interview)
- Knowledge of monitoring health and wellbeing using various methods (cv)
- Experience of delivering exercise sessions to clinical populations (cv and interview)
- Able to handle multiple simultaneous demands and activities (cv
This studentship involves training, supervising, working with and/or being in sole charge of children and young people. The successful applicant will therefore be required to apply for a disclosure from the Disclosure and Barring Service (DBS). A disclosure is an impartial and confidential document that details an individual’s criminal record and where appropriate gives details of those who are banned from working with children. Having a criminal record will not necessarily be a bar to obtaining a position.
How do I Apply?
For an informal discussion about this opportunity please email Dr Ian Lahart email@example.com or Dr Mark Burnley firstname.lastname@example.org
Applicants should email a CV and covering letter detailing their suitability for the project and contact details of two referees to email@example.com. Please clearly indicate the reference “PhD EDGE Cancer” in the title of the email and on your cover letter.