Experimental Investigation of Pharmaceutical Tablet manufacturing

This project aims to identify critical material attributes and critical process parameters for pharmaceutical tablet manufacturing. Specific tasks for this project include but not limited to undertake critical literature review to understand the background, the state-of-the-art and the challenges, and to identify the knowledge gap; to carry out experimental investigation to understand how properties of pharmaceutical formulations applicable to assess tabletting performance can be measured, and to explore the influence of powder properties and process conditions on pharmaceutical tablet manufacturing.

Our aim is to develop science-based predictive models, design tools and innovative manufacturing processes for formulated products. This is underpinned by our active research in particulate materials manufacturing, multiphase flow, advanced numerical modelling using coupled discrete element methods with computational fluid dynamics (DEM-CFD) and finite element modelling (FEM), process modelling and optimisation, and measurements and characterisation using advanced techniques.

Supervisor: Charley Wu

Entry requirements

Open to UK and international students starting in April 2023.

You will need to meet the minimum entry requirements for our Chemical and Process Engineering PhD programme.

We are looking for a highly motivated candidate who holds a master degree or equivalent in Engineering, pharmaceutics, or a closely-related discipline, with a keen interest in pharmaceutical engineering. The candidate should be a good team player and can engage in collaboration with good oral and written communication skills. Previous experience or some knowledge in particle technology are desirable but not essential as training will be provided. 

6.5 overall with 6.0 in each band or equivalent IELTS requirements.

How to apply

In the first instance, please email a copy of CV, and/or transcripts to Prof. Charley Wu, before submitting your formal application.

Applications should be submitted via the Chemical and Process Engineering programme page.

Funding notes

Home student tuition fees will be covered, plus a stipend of £17,668 per year. Funding is for 3 years. Funded by Alkermes.