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  Experimental system for planning and evaluating cardiac surgery


   Department of Mechanical Engineering

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  Dr D Espino  Applications accepted all year round  Awaiting Funding Decision/Possible External Funding

About the Project

The aim of the project is to design and develop an effective experimental system for planning of cardiac surgery, with a focus on planning for mitral heart valve surgery. Morphometry will form of a central part in this process of design and development, including effective mechanisms by which to incorporate this individual variable at the surgical planning stage. This PhD targets this gap in healthcare technology.

The intention is for the system to enable hydrodynamic testing of planned surgery, potentially using biological heart valve ex vivo, to evaluate the effectiveness of the surgery. This may require design considerations across a range of scales, from organ to valve and potentially smaller scales too. The device should be complementary with materials testing, such as Dynamic Mechanical Analysis and quasi-static testing for material’s characterisation of cardiac tissues including elastic, viscoelastic and hyperelastic formulations. All outputs should be compatible with finite element analysis simulations.

Engineering (12)

Funding Notes

There may be potential for some applicants to apply for a School of Engineering scholarship, if they meet the scholarship criteria. Self-funded PhD students are welcome too. Potential applicants are encouraged to contact Dr Espino ([Email Address Removed]).

References


DC de Oliveira et al. 2021. A toolbox for generating scalable mitral valve morphometric models. Computers in Biology and Medicine 135, 104628
See: https://www.sciencedirect.com/science/article/abs/pii/S0010482521004224


R Northeast et al., 2021. Mechanical testing of glutaraldehyde cross-linked mitral valves. Part one: In vitro mechanical behaviour. Journal of Engineering in Medicine 235, 281-290.
See: https://journals.sagepub.com/doi/pdf/10.1177/0954411920975894

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