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Click here to search FindAPhD.com for PhD studentship opportunitiesAbout the Project
Institute and team: You would be part of a dynamic research group with a solid track record, and located in an excellent scientific environment, the Department of Immunology (Head: Prof. Dr. Hans-Georg Rammensee) located on the University and University Hospital campus of Tübingen. In our lab you would find a friendly, well-connected and international environment, a firm commitment to good supervision and professional development, and an excellent instrumental setup. International applicants are very welcome and will be supported in participating in German courses (NB: German skills are not a requirement for application as English will generally be used in the work environment).
Funding Notes
Your profile: an excellent Masters degree in biology or medicine, and research experience in molecular/cellular biology, microbiology/virology, protein biochemistry or immunology. You are highly motivated to work independently and also as part of a team. You have very good written + spoken English.
Your application: The starting date is flexible. The following documents are mandatory - only complete electronic applications will be reviewed on an ongoing basis:
- Cover/motivation letter (max 1 A4)
- CV
- Transcripts/certificate of diploma and bachelor degree
- Support letter from 1 previous supervisor
References
1. Wang H, Flannery SM, Dickhöfer S, Huhn S, George J, Kubarenko AV, Lascorz J, Bevier M, Willemsen J, Pichulik T, Schafmayer C, Binder M, Manoury B, Paludan SR, Alarcon-Riquelme M, Bowie AG, Försti A, Weber AN. A coding IRAK2 variant compromises TLR signaling and is associated with colorectal cancer survival. J Biol Chem. 2014 Jun 19. pii: jbc.M113.492934.
2. Colak E, Leslie A, Zausmer K, Khatamzas E, Kubarenko AV, Pichulik T, Klimosch SN, Mayer A, Siggs O, Hector A, Fischer R, Klesser B, Rautanen A, Frank M, Hill AVS, Manoury B, Beutler B, Hartl D, Simmons A, Weber AN. RNA and Imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events. J Immunol. 2014 Jun 15;192(12):5963-73.
4. Klimosch SN, Försti A, Eckert J, Knežević J, Bevier M, von Schönfels W, Heits N, Walter J, Hinz S, Lascorz J, Hampe J, Hartl D, Frick JS, Hemminki K, Schafmayer C, Weber AN. Functional TLR5 genetic variants affect human colorectal cancer survival. Cancer Res 2013;73(24):7232-42.
5. Eckert KJ, Kim YJ, Kim JI, Gürtler K, Oh D-Y, Sur S, Lundvall L, Hamann L, van der Ploeg A, Pickkers P, Giamarellos-Bourboulis E, Kubarenko AV, Weber AN, Kabesch M, Kumpf O, An H-J, Lee J-O and Schumann RR. The Crystal Structure of Lipopolysaccharide Binding Protein Reveals the Location of a Frequent Mutation that Impairs Innate Immunity. Immunity 2013; 39(4):647 – 660.
6. Kawai, T. & Akira, S. Toll‐like Receptors and Their Crosstalk with Other Innate Receptors in Infection
and Immunity. Immunity 34, 637‐650 (2011).