Developing human cardiac organoids that fully mimic the structural and functional features of the native organ and are capable of mimicking dynamic progression of human cardiac diseases could produce breakthroughs in cardiovascular research. In this project we will design and fabricate mesh electronics with integrated biosensors to create optimum 3D human cardiac organoids with mature features and integrated monitoring capabilities. Electrical, biological and molecular signals from living cells will be studied in control cardiac organoids and organoids modelling cardiac disease.
Applicants with background in electrophysiology/tissue engineering and/or electronics/nanofabrication are particularly encouraged to apply. The successful candidate will also have the opportunity to collaborate closely with the National Physical Laboratory (NPL).
Applicants should select the Biosciences and Medicine PhD programme.
The project is highly interdisciplinary in a cutting-edge area of research at the interface between biology and electronics. The PhD student will gain expertise in electronic engineering, electrophysiology, cell culture, imaging and molecular methodologies.
The research will be performed within a vibrant and dynamic environment in the laboratories of Dr Patrizia Camelliti, Dr Yunlong Zhao and Prof Fernando Castro at the School of Biosciences and Medicine and the Advanced Technology Institute at University of Surrey and NPL.
A 3.5-year fully funded studentship open to applicants worldwide starting in October 2022. Funding includes stipend, full fees and a research grant.
More information on the School of Biosciences and Medicine and the Advanced Technology Institute
Entry requirements
A First or Upper Second-Class Honours degree from the UK (or equivalent qualification from international Institutions) or Masters degree in a relevant subject area.
English language requirements: An IELTS Academic of 6.5 or above with 6 in each individual category (or equivalent qualification from other agencies).
How to apply
Applications should be submitted via the online application portal for Biosciences and Medicine PhDs.
This project is part of the Faculty-funded studentship scheme and you can express interest in one or two of the projects available via this scheme. When completing your application, in place of a research proposal, please provide a 1-page (maximum) document containing the reference numbers(s), project title(s) and supervisor name(s) of the project or two projects you have selected, together with an explanation of your motivations for wanting to study for a PhD and your reasons for selecting the project(s) you have chosen.
The reference number for this project is FHMS PL - BM - 06.
For those interested in the project described above, we strongly encourage informal enquiries to be sent to Dr Patrizia Camelliti ([Email Address Removed]).
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