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Project is eligible for funding under the FBS Faculty Studentships scheme. Successful candidates will receive a PhD studentship for 4 years, covering fees at UK/EU level and stipend at research council level (£14,777 for 2018-19).
Candidates should have, or be expecting, a 2.1 or above at undergraduate level in a relevant field. If English is not your first language, you will also be required to meet our language entry requirements. The PhD is to start in Oct 2018.
Please apply online here https://studentservices.leeds.ac.uk/pls/banprod/bwskalog_uol.P_DispLoginNon Include project title and supervisor name, and upload a CV and transcripts.
1) Foresti O, Denecke J. (2008). Intermediate organelles of the plant secretory pathway: identity and function. Traffic 9: 1599–1612
2) Rojo E, Denecke J. (2008). What is moving in the secretory pathway of plants? Plant Physiol. 147(4):1493-503.
3) Snowden CJ, Leborgne-Castel N, Wootton LJ, Hadlington JL, Denecke J.(2007). In vivo analysis of the lumenal binding protein (BiP) reveals multiple functions of its ATPase domain. Plant J. 52(6):987-1000.
4) Foresti, O., daSilva, L.L.P. and Denecke, J. (2006). Overexpression of the Arabidopsis Syntaxin PEP12/SYP21 Inhibits Transport from the Prevacuolar Compartment to the Lytic Vacuole in Vivo. The Plant Cell, 18, 2275–2293.
5) DaSilva, L.L.P., Foresti, O., and Denecke, J. (2006). Targeting of the plant vacuolar sorting receptor BP80 is dependent on multiple sorting signals in the cytosolic tail. The Plant Cell, 18, 1477–1497
6) Pimpl, P., Taylor, J.P., Snowden, C.J., Hillmer, S., Robinson, D.G. Denecke, J. (2006). Golgi-Mediated Vacuolar Sorting of the Endoplasmic Reticulum Chaperone BiP May Play an Active Role in Quality Control within the Secretory Pathway. The Plant Cell, 18, 198–211.
7) DaSilva, L.L., Taylor, J.P., Hadlington, J.L., Hanton, S.L., Snowden, C.J., Fox, S.J., Foresti, O., Brandizzi, F., and Denecke, J. (2005). Receptor salvage from the prevacuolar compartment is essential for efficient vacuolar protein targeting. The Plant Cell 17, 132-148.
8) Luis L.P. daSilva, Erik L. Snapp, Jürgen Denecke, Jennifer Lippincott-Schwartz, Chris Hawes, and Federica Brandizzi (2004) Endoplasmic reticulum export sites and Golgi bodies behave as single mobile secretory units in plant cells. The Plant Cell 16, 1735-1771.
9) Pimpl, P., Hanton, S. L., Taylor, J.P., Pinto-daSilva, L.L., and Denecke, J. (2003). The GTPase ARF1p Controls the Sequence-Specific Vacuolar Sorting Route to the Lytic Vacuole. The Plant Cell 15, 1242-1256.
10) Hadlington, J. L., Santoro, A., Nuttall, J., Denecke, J., Ma, J. K.Vitale, A., Frigerio, L. (2003). The C-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole. Mol Biol Cell 14, 2592-2602.
11) Brandizzi, F., Hanton, S., DaSilva, L. L., Boevink, P., Evans, D., Oparka, K., Denecke, J., Hawes, C. (2003). ER quality control can lead to retrograde transport from the ER lumen to the cytosol and the nucleoplasm in plants. Plant Journal 34, 269-281.
FTE Category A staff submitted: 60.90
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