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  Formulation and manufacture of Lipid Nanoparticles - fuelling the next generation of mRNA vaccines


   Strathclyde Institute of Pharmacy & Biomedical Sciences

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  Prof Y Perrie  No more applications being accepted  Competition Funded PhD Project (UK Students Only)

About the Project

Are you a person who has a passion for science and working across multiple scientific disciplines? Are you someone who wants to research cutting edge technology and delve into formulating nanomedicines to enhance drug delivery? Are you looking for an exciting opportunity to work between academic and industrial sectors? Then this is an ideal opportunity for you.

 We are looking for applicants to join our exciting collaboration that will focus on the formulation, production and scale-up of lipid nanoparticles (LNPs), to improve manufacturing processes, process scalability and ease of manufacture of this increasingly important therapy. This exciting opportunity is to immerse yourself in a rapidly evolving field and work within a world leading nanomedicine research laboratory, led by Prof Yvonne Perrie, within the University of Strathclyde. You will be supervised by Professor Perrie, a globally acknowledged expert in drug and vaccine delivery, and Micropore Technologies Ltd, with customers around the world, whose well-established crossflow micromixing technology has been further developed to give highly tuneable, reproducible, and scalable nanoparticle development and manufacturing processes.  

 This project aims to develop a thorough understanding of the effect of the process parameters and fluid mixing dynamics within the range of Micropore’s crossflow devices to support the fast and easy scale-up of LNP and other nanoparticle production processes, helping to increase access to these emerging technologies. By joining this collaboration, you will gain a unique insight into world-class academic research coupled with world-class industry experience in the fields of lipid nanomedicine formulation, characterisation and manufacturing.  Micropore’s vision is to enable local vaccine manufacture, including in developing countries.

 As a PhD student at the Strathclyde Institute of Pharmacy and Biomedical Sciences, you will work in a leading institute for research and training focused on discovering, developing, and delivering nanomedicines. The university is situated right in the heart of Glasgow, which National Geographic names as one of its 'Best of World Destinations' and one of the world's friendliest cities by Rough Guide readers. You will also benefit from an additional postgraduate researcher certification from the University of Strathclyde.

 This truly is an amazing time to research lipid nanomedicines coupled with an exciting industrial collaboration. This project is ideally suited to a highly-motivated and talented student with a keen interest to work within drug delivery. Prospective candidates should have at least an upper second class degree (or equivalent) in pharmacy, pharmaceutical sciences, biosciences or engineering backgrounds. Through this PhD, you will receive highly desirable training in many LNP production and analytical techniques both at the university and at Micropore Technologies.

 We welcome interested candidates and look forward to hearing from you. Informal enquires can be made to Professor Perrie [Email Address Removed]


Biological Sciences (4) Engineering (12) Medicine (26)

Funding Notes

This is a Strathclyde CDT fully funded project for home funded students 3.5 years duration including a EPSRC stipend

Where will I study?

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