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Fully Funded MSc by Research in Cardiovascular and Diabetes Medicine: Defining insulin resistance in the brain and impact on cognition


   School of Medicine, Medical Sciences & Nutrition

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  Prof Mirela Delibegovic, Dr C Sutherland, Prof B Platt, Dr Nicola Morrice  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

The North-East Scotland (NES) Diabetes and Cardiovascular Research Alliance Masters Training Programme (MTP) in cardiovascular and diabetes medicine is an exciting new programme that will expand interdisciplinary cardiovascular and diabetes research between the University of Aberdeen and the University of Dundee.

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It is known that there is a relationship between diabetes, nutrition, cognitive function and neurodegenerative disorders e.g. dementia and Alzheimer’s disease. This Masters by research project will examine how dysregulation of the insulin signalling pathway in the brain can contribute to neurodegenerative disorders. The student will use a range of cell culture models including primary neuronal cultures, neuronal cell lines as well as in vivo preclinical models to delineate which actions of insulin on the brain contribute to both, metabolic and neurodegenerative disorders.

Informal project enquiries are encouraged. Please contact Professor Mirela Delibegovic ([Email Address Removed]) for more information.

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This opportunity to achieve an MSc by Research is part of a flagship collaborative programme between the two universities. Based either in Aberdeen or Dundee but with cross-institutional training opportunities, students will be embedded in vibrant multidisciplinary research teams with a mix of cardiovascular/diabetes clinicians and scientists. Excellent research training opportunities are provided, including MTP specific training events, and more general training and educational activities in the universities, highlighted for example by the newly established Doctoral Academy in Dundee.

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ENTRY REQUIREMENTS & ELIGIBILITY

Applicants must possess or be expected to possess by the time of starting the MSc, at least one of the following:

  • First class, or upper second-class UK Honours Degree (or international equivalent) in a relevant scientific discipline.
  • Postgraduate Masters degree in a relevant scientific discipline, or equivalent.

International applicants may apply for this studentship but will have to find additional funding to cover the difference between overseas and home fees (~£18,000 per annum).

International applicants receiving a funded offer of study covering UK fees only will be asked to provide evidence that this fee difference can be met.

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APPLICATION PROCEDURE

  • Full application instructions and further information can be found by visiting the following link: Masters Training Programme
  • CV's submitted directly through a FindAPhD enquiry WILL NOT be considered.
  • If you have further questions, please email [Email Address Removed]

Funding Notes

This one-year MSc by Research is funded by the North-East Scotland Diabetes and Cardiovascular Research Alliance.
Funding for this project will cover home/UK fees (this includes EU nationals that hold UK settled or pre-settled status), research costs, and a stipend at the UKRI rate (£16,062 for the 2022/2023 academic year).
International applicants may apply for this studentship but will have to find additional funding to cover the difference between overseas and home fees (~£18,000 per annum). International applicants receiving a funded offer of study covering UK fees only will be asked to provide evidence that this fee difference can be met.

References

1) Souza Matos, M., Platt, B., & Delibegović, M. (2021). Effects of dietary restriction on metabolic and cognitive health. Proceedings of the Nutrition Society, 80(2), 126-138. doi:10.1017/S0029665120007910
2) Dekeryte R, Hull C, Plucińska K, Khan S, Kamli-Salino S, Mody N, Morrice N, McLaughlin C, Gault V, Platt B, Delibegovic M. (2019) Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice. Biochem Pharmacol. 166:222-230. doi: 10.1016/j.bcp.2019.05.020.
3) Morrice, N., van Aalten, L., McNeilly, A. et al. (2020) Reducing Glut2 throughout the body does not result in cognitive behaviour differences in aged male mice. BMC Res Notes 13, 438. doi: 10.1186/s13104-020-05276-y
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