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  Future-proofing our food: exploiting landrace diversity for more efficient andresilient wheat


   Department of Biology

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  Dr A Harper, Prof Ian Bancroft  No more applications being accepted  Competition Funded PhD Project (European/UK Students Only)

About the Project

To ensure global food security, crop breeders must develop varieties which are
more productive as well as more resilient to the potential impacts of climate
change. Bread wheat (Triticum aestivum) is the most important grain source for
humans, but the intensive breeding of the green revolution, whilst saving billions
of lives, led to a huge bottleneck in genetic diversity. This means that traits such
as heat and drought tolerance, which could become vital breeding targets in the
next few decades, may need to be introduced back into the breeding pool from

additional sources. Global landrace collections, made up of traditional, locally-
adapted varieties, may be a good place to look for wheat lines that can tolerate

heat and drought stress, and if the genetic variants underlying these traits can
also be isolated, then introgression back into elite cultivars will be more efficient.
The recent development of an Associative Transcriptomics platform based on
landrace wheat accessions by the Harper/Bancroft labs, provides an excellent
resource for associating trait variation with gene sequence (SNP) and expression
(GEM) markers. During this project, the student will phenotype the landraces
for their response to heat and drought, before using Associative Transcriptomics
to identify genetic markers associated with them. These markers will be validated
for use in marker-assisted selection, and will be used to propose candidate genes
and reveal the mechanisms underlying these traits.
This project offers the opportunity to apply a new statistical genetics approach
to important breeding targets in bread wheat for the first time, and would suit a
student who is interested in pursuing a project which combines glasshouse,
laboratory and bioinformatics activities.


Funding Notes

Funding: This is a 4 year fully-funded studentship part of the BBSRC White Rose Doctoral Training Partnership in Mechanistic Biology. The studentship covers: (i) a tax-free stipend at the standard Research Council rate (around £15,000 per year), (ii) tuition fees at UK/EU rate, (iii) research consumables and training necessary for the project.

Entry requirements: At least an upper second class honours degree, or equivalent in any biological, chemical, and/or physical science. Students with mathematical backgrounds who are interested in using their skills in addressing biological questions are also welcome to apply.

References

Eligibility: The studentships are available to UK and EU students who meet the UK residency requirements. Students from EU countries who do not meet the residency requirements may still be eligible for a fees-only award. Further information about eligibility for Research Council UK funding

Shortlisting: Applicants will be notified if they have been selected for interview in the week commencing on Monday 28 January 2019.

Interviews: Shortlisted applicants will be invited for an interview to take place in the Department of Biology at the University of York on Wednesday 6 and Thursday 7 February 2019. Prior to the interview candidates will be asked to give a 5 minute presentation on a research project carried out by them.

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