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Our main deadline for applications for funded places has now passed. Supervisors may still be able to consider applications from students who have alternative means of funding (for example, charitable funding, clinical fellows or applicants with funding from a foreign government or equivalent). Prospective applicants are strongly advised to contact their prospective supervisor in advance of making an application.
Please note that any applications received after the main funding deadline will not be assessed until all applications that were received by the deadline have been processed. This may affect supervisor availability.
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions. Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ. Nat Commun. 2017
Between form and function: the complexity of genome folding. Oudelaar AM, Hanssen LLP, Hardison RC, Kassouf MT, Hughes JR, Higgs DR.. Hum Mol Genet. 2017
Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR et al. 2017. Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo. Nat Cell Biol 19: 952-961.
Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Oudelaar AM, Sharpe ja, Suciu M, Telenius J, Williams R, Rode C, Li P-S, Pennacchio LA, Sauka-Spengler T, Sloane-Stanley JA, Ayyub H, Butler S, Gibbons RJ, Smith AJH, Wood WG & Higgs DR (2016) Testing the super-enhancer concept by in-vivo dissection. Nature genetics, 48, 895-903.
Hughes, J.R., Roberts, N., McGowan, S., Haay, D., Giannoulatou, E., Lynch, M., de Gobbi, M., Taylor, S., Gibbons, R. & Higgs, D.R. (2014) Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment. Nat Genet, 46: 205-212.
Kowalczyk, M., S., Hughes, J.R., Garrick, D., Lynch, M.D., de Gobbi, M., McGowan, S.J., Brown, J.M., Hosseini, M., Sharpe, J.A., Sloane-Stanley, J.A., Gray, N.E., Collavin, L., Gibbons, R.J., Flint, J., Taylor, S., Buckle, V.J., Wood, W.G. & Higgs, D.R. (2012) Intragenic enhancer-like elements act as alternative promoters. Mol Cell, 45, 447-458
FTE Category A staff submitted: 238.51
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