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Genetics of vascular diseases: Identification of novel genes that cause Vascular Anomalies

  • Full or part time
  • Application Deadline
    Wednesday, May 01, 2019
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

You will work on a research project with the following objectives:
• Identify a Vascular Anomaly-causative gene using NGS
• Validate the effects of identified gene-mutations on function of the encoded protein in vitro
• Identify molecular mechanisms, read-outs, and potential therapeutic targets in a cellular model of disease
• Generate and characterize a zebrafish model of disease by gene knock-in (if gain of function)/ knock-down (if loss of function)
• Identify genotype-phenotype correlations
You will also take part in the international training programme of the network and participate in various networking and outreach events.

Requirements

We are looking for a motivated student with a strong commitment to basic and/or translational research, who:
• is eligible for MSCA-ETN funding, see Funding Notes.
• has a MSc degree in biology, biomedical sciences or related disciplines
• is a team player with good communication skills

Appointment terms

The successful candidate will receive an attractive salary in accordance with MSCA regulations for Early Stage Researchers. The period of employment is 3 years. Starting date: June – October 2019.

How to apply

– Make sure you meet the qualifying requirements.
– Submit your application to by e-mail, mentioning ‘application for ESR1/2’ in the subject line. Please send one pdf file containing:
• A motivation letter describing your research career goals, skills and experience (cover letter)
• Curriculum vitae
• Grade transcripts and BSc/MSc diploma (in English or with a translation into English)
• Two letters of recommendation or the contact information for at least 2 referees.

Deadline for submitting applications: 1 May 2019

More information

Please visit http://www.vacure.eu for more information on the project, the recruitment process and selection criteria. Contact for questions:

Funding Notes

To be eligible for this H2020-MSCA-ITN funded PhD student position, you must:
– not have resided or carried out your main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account, and
– At the date of recruitment (=first day of employment), be in the first four years (full-time equivalent research experience) of your research career and not have been awarded a doctoral degree.

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