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Glycobiology of human gut microbes

   Institute of Microbiology and Infection

  Dr Lucy Crouch, Dr P Moynihan  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Research interests/description of main research theme:

The Crouch Lab is looking for enthusiastic PhD students interested in the glycobiology of human gut microbes, including pathogens. The overall aims are to understand more about the host-microbe interactions in the gut and cross-feeding of host glycans between different microbes. Therefore, the main focus of the project will be on characterising the activities and specificities of carbohydrate-active enzymes (CAZymes) from different microbes. There will be opportunities to work with different species of bacteria and learn a variety of techniques. The work will involve predominantly host-type glycans, such as N- and O-glycans.

Person Specification

Applicants should have a strong background in biochemistry, and ideally a background in microbiology. They should have a commitment to research in glycobiology and hold or realistically expect to obtain at least an Upper Second Class Honours Degree in a relevant subject.

How to apply

Informal enquiries should be directed to

Applications should be directed to       (email     ). To apply, please send:

•             A detailed CV, including your nationality and country of birth;

•             Names and addresses of two referees;

•             A covering letter highlighting your research experience/capabilities;

•             Copies of your degree certificates with transcripts;

•             Evidence of your proficiency in the English language, if applicable.

Funding Notes

Self-funded PhD students only


Briliute J, et al. (2019) Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nature microbiology 4(9):1571-1581.
Crouch LI, et al. (2020) Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown. Nature communications 11(1):4017.

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