Harnessing data from wearable devices for the prognosis of long-term conditions and mortality: application to clinical risk scores


   Department of Population Health Sciences

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  Dr T Yates, Dr F Zaccardi, Dr Alex Rowlands  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

We invite applicants for a 4-year iCASE studentship to work in collaboration with our industrial partner Reinsurance Group of America (RGA) UK Services Limited

How we lead our lives effects our health, yet this information is typically not considered when predicting future risk of chronic disease or mortality. For example, an individual with a high genetic risk of a disease or a high risk based on routine clinical data is placed in the same high risk pool regardless of how physically active they are, despite the fact that physical activity can modify much of this risk for some long-term conditions and mortality outcomes. The studentship will include training in cutting edge analytical approaches for using data gathered from wrist worn accelerometers (similar to those found in smart watches and physical activity trackers) in generating patterns of physical behaviours, ranging from sleep to physical activity. The relevance of these novel metrics to predicting the onset of common chronic disease or early mortality will then be explored using flexible parametric models, which will include developing new risk prediction tools. This studentship includes an industry placement.

Enquiries

Project Enquiries to [Email Address Removed]

Programme enquiries to [Email Address Removed]

To apply please refer to

https://more.bham.ac.uk/mrc-aim/phd-opportunities/


Biological Sciences (4) Mathematics (25) Medicine (26) Nursing & Health (27) Physics (29) Sport & Exercise Science (33)

Funding Notes

The competition funding provides students with:
4 years of stipend at UKRI rates
4 years of tuition fees at UK fee rates (Plus one award of a full overseas fee waiver to an international applicant)*
RTSG
Budget to help with the cost of purchasing a laptop
The University of Leicester will provide full overseas fee waivers for the duration of their study to all international students accepted at Leicester. The funder, UKRI, allows us to appoint up to 30% overseas students.

References

1) Dempsey PC, Rowlands AV, Strain T, Zaccardi F, Dawkins N, Razieh C, Davies MJ, Khunti KK, Edwardson CL, Wijndaele K, Brage S. Physical activity volume, intensity, and incident cardiovascular disease. European Heart Journal. 2022 Dec 7;43(46):4789-800.
2) Argyridou S, Zaccardi F, Davies MJ, Khunti K, Yates T. Walking pace improves all-cause and cardiovascular mortality risk prediction: A UK Biobank prognostic study. European journal of preventive cardiology. 2020 Jul 1;27(10):1036-44.
3) Zaccardi F, Timmins IR, Goldney J, Dudbridge F, Dempsey PC, Davies MJ, Khunti K, Yates T. Self-reported walking pace, polygenic risk scores and risk of coronary artery disease in UK biobank. Nutrition, Metabolism and Cardiovascular Diseases. 2022 Nov 1;32(11):2630-7.