About the Project
To this end, we have developed a novel tool, which can apply force to samples through the use of magnets attached on to a microplate lid. This tool provides a unique opportunity to merge high-throughput screening with mechanics. Forces have large impact upon the activity of many proteins therefore it may be possible to specifically “drug” a protein only when it is mechanically activated. This project is focused upon optimising and applying this tool to mechanically sensitive cellular proteins.
Candidates must have a first or upper second-class honors degree or equivalent overseas qualification in a relevant subject.
Interested candidates should in the first instance contact Dr Chris Toseland [Email Address Removed]
How to apply:
Please complete a University Postgraduate Research Application form available here: www.shef.ac.uk/postgraduate/research/apply
Please clearly state the prospective main supervisor in the respective box and select ‘Department of Oncology and Metabolism’ as the department.
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