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Home-based exercise in chronic kidney disease


Project Description

Patients with Chronic Kidney Disease (CKD) frequently suffer from muscle wasting, fatigue and poor physical function which lead to poor outcome, reduced quality of life and high healthcare costs. Our group has shown that supervised resistance exercise is an effective approach to improving muscle mass and physical function1,2, but in-centre programmes are not sustainable in the longer term. This PhD project will 1) carry out a systematic review of the literature; 2) using a mixed-methods approach, explore the patient and healthcare staff perspectives of muscle mass, strength and function, the role of resistance training, and the requirements for an acceptable home-based programme; 3) design an intervention via an iterative co-production process; and 4) carry out a feasibility trial of home-based resistance exercise in CKD.

Entry requirements

Applicants are required to hold/or expect to obtain a UK Bachelor Degree 2:1 or better in a relevant subject. The University of Leicester English language requirements apply where applicable.

How to apply

You should submit your application using our online application system: https://www2.le.ac.uk/research-degrees/phd/applyphd

Apply for a PhD in Health Sciences
In the funding section of the application please indicate you wish to be considered for a HS_CLS Studentship
In the proposal section please provide the name of the supervisor and project you want to be considered for.

Project / Funding Enquiries:
Application enquiries to

Funding Notes

The studentship funding covers:
Fees - full-time PhD Registration Fees at H/EU rates for three years
Student stipend based on the RCUK rate (currently £14,777 for 2018/19)
Research Training Support will available

References

1. EL Watson, NJ Greening, JL Viana, J Aulakh, DH Bodicoat, J Barratt, J Feehally and AC Smith. Progressive Resistance Exercise Training in Chronic Kidney Disease: A Feasibility Study. Am J Kidney Dis 2015, 66(2):249-57.
2. Watson EL, Gould DW, Wilkinson TJ, Xenophontos S, Clarke AL, Vogt BP, Viana JL, Smith AC. 12 weeks combined resistance and aerobic training confers greater benefits than aerobic alone in non-dialysis CKD. American Journal of Physiology-Renal Physiology 2018 DOI: 10.1152/ajprenal.00012.2018.

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