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HORNBERGERM_U23FMH ‘Sweet Memories’ – Continuous glucose monitoring and cognitive impairment in in-patient diabetes


   Norwich Medical School

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  Prof M Hornberger  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

Background   

Management of diabetes has been revolutionised over the last years with the advent of continuous glucose monitoring (CGM), which allows monitoring of one’s glucose levels via a sensor patch on the skin. CGM has gained increasing popularity for people with diabetes in the community. However, CGM has been less consistently used for in-hospital-patients with diabetes, despite it potentially allowing better management of patients, in particular those with cognitive impairment. The current project will investigate whether CGM for in-hospital-patients with diabetes and cognitive impairment can improve their health management and reduce their hospital stay.  

Training 

The study will be conducted as a collaboration between the Norwich Medical School and the Norfolk and Norwich University Hospital. At admission, eligible patients will be randomly allocated to either receiving a CGM sensor or not. We will measure patients’ time in range as the main outcome measure until they are deemed fit for discharge, in addition to other factors, such as fidelity of CGM sensor data, patient and staff satisfaction, cognitive impairment and medication changes.  

Training 

The successful candidate will be trained in an exciting, interdisciplinary research area of diabetes and dementia, two of the most common age-related diseases in the UK. The student will be responsible for the design, set-up and running of the study, under the guidance of the supervisory team. There will be ample opportunity to learn about the patients’ experiences, as well as the staffs’. We will also provide statistical training and data driven artificial intelligence approaches for the CGM sensor data. 

Person specification 

We are looking for an enthusiastic student with a background in medicine, health sciences, endocrinology, neuroscience, data science or related fields. It is essential for this project to have outstanding inter-personal skills, since the project requires interaction with cognitively impaired patients, as well as liaison with medical and healthcare professionals. You will be required to a have an enhanced Disclosure and Barring Service check, which can be arranged at the start of the start, due to the vulnerable people you will interact with. Training for all others aspects of the project will be provided. 


Funding Notes

This PhD project is in a Faculty of Medicine and Health Sciences competition for funded studentships. These studentships are funded for 3 years and comprise UK fees, an annual stipend of £17,668 and £1,000 per annum for research training (RTSG). Overseas applicants (including EU) may apply but are required to fund the difference between Home and International tuition fees.

References


Mattishent K, Lane K, Salter C, Dhatariya K, May HM, Neupane S, et al. Continuous glucose
monitoring in older people with diabetes and memory problems: a mixed-methods feasibility study in the UK.
BMJ Open. 2019;9(11):e032037
Mattishent K, Richardson K, Dhatariya K, Savva GM, Fox C, Loke YK. The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: A retrospective cohort study. Diabetes Obes Metab. 2019 Sep;21(9):2076-2085. doi: 10.1111/dom.13769.
Galindo RJ, Dhatariya K, Gomez-Peralta F, Umpierrez GE. Safety and efficacy of inpatient diabetes management with non insulin agents: an overview of international practices. Current Diabetes Reports 2022;22:237-246
Dhatariya K, Mustafa OG, Rayman G. Safe care for people with diabetes in hospital. Clinical Medicine 2020;20:21-27
Ambikairajah A, Tabatabaei-Jafari H, Walsh E, Hornberger M, Cherbuin N. Longitudinal Changes in Fat Mass and the Hippocampus. Obesity. 2020 Jul;28(7):1263-1269.
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