Host-pathogen interaction during parasite infection using organoid models at University of the West of Scotland on FindAPhD.com

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Dr Stuart Woods No more applications being accepted Self-Funded PhD Students Only

About the Project

Stem cell derived tissue organoids is a cell culture method which generates a physiologically accurate 3D model of organs in an in vitro setting. Such models include brain, ocular and gut tissues. At UWS we aim to use this in vitro technique to study host pathogen interaction during parasitic infections such as Toxoplasma gondii and Acanthamoeba. These are single cell parasitic organisms which can have a dramatic impact on human health and our aim is to better understand how they infect the host, the impact of infection and study potential treatments.

During the research, the candidate will work with a range of parasitic organisms including Acanthamoeba and T. gondii. They will also have experience working with murine stem cell cultures. Analysis techniques will include transcriptomics, metabolomics, cell-based assays and bioinformatics.

We are proud that our research interests of the centre maps UN SDG 3, Good Health and Well-being.

The candidate will have strong interest in infectious disease and knowledge and good understanding of cell culture techniques

Programme start date: 1st October 2023

References

In the first instance, informal enquiries should be made by email to Dr Stuart Woods (Stuart.Woods@uws.ac.uk). Successful applicants will be asked to submit the application through the UWS online system (https://www.uws.ac.uk/study/research-degrees/admissions-application/)