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How do antibiotics affect the human gut microbiota? (JUGEQ20DTP2)

   Graduate Programme

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  Prof N Juge  No more applications being accepted  Competition Funded PhD Project (European/UK Students Only)

About the Project

This PhD studentship provides an exciting opportunity for the successful candidate to address
fundamental questions on the role of antibiotics on the gut microbiota and acquire state-of-the art in both in silico and in vivo approaches.

The human body harbours a diverse and dense population of commensal bacteria which exert key
functions in terms of human health. Antibiotics remain the major treatment for bacterial infections but also affect the composition of the human gut microbiota with potential side-effects. It is therefore critical to understand the precise mechanisms of how antibiotics may affect the transient shifts in microbial communities, recovery process of the gut microbiome, and mechanisms driving outgrowth or loss of bacterial species during/post antibiotic treatment.

The PhD student will be based at the Quadram Institute Bioscience where he/she will receive training in relevant experimental models and state-of-the art bioinformatics tools for the analysis of gut microbiota communities and benefit from complementary expertise un computational modelling approaches at the Earlham Institute.

The student will benefit from the established network of international collaborations of the host Labs in these this research area. Training will embrace research practice and theory, management,
communication (to scientific and lay audiences), intellectual property, teamwork and technical writing. The student will present his/her work to internal seminars and to relevant Microbiology International meetings. The possible commercial issues relating to the impact of this research on human health will be highlighted and the student will be encouraged to participate into outreach activities and innovative competitions.

This project has been shortlisted for funding by the Norwich Biosciences Doctoral Training Partnership (NRPDTP). Shortlisted applicants will be interviewed as part of the studentship competition. Candidates will be interviewed on either the 7th, 8th or 9th January 2020.

The NRP DTP offers postgraduates the opportunity to undertake a 4-year research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship (PIPS) during their study. The internship offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second-class honours degree, or equivalent, are invited to apply.

For further information and to apply, please visit our website:

Funding Notes

For funding eligibility guidance, please visit our website: Full Studentships cover a stipend (2019/0 rate: £15,009pa), research costs and tuition fees at UK/EU rate and are available to UK and EU students who meet the UK residency requirements.

Students from EU countries who do not meet the UK residency requirements may be eligible for a fees-only award. Students in receipt of a fees-only award will be eligible for a maintenance stipend awarded by the NRPDTP Bioscience Doctoral Scholarships. To be eligible students must meet the EU residency requirements.
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