About the Project
We recently published a study (Kendall et al., 2019 NAR) identifying novel structural elements within the RNA genome of Chikungunya virus. While the RNA structures are essential for efficient replication of the virus genome, evidence suggests that they are under different selection pressures in their human and mosquito host-cells. This project will use cutting edge molecular virology, genomics and structural methods to investigate mechanisms by which RNA structure in the Chikungunya virus genome functions in human and mosquito host cells.
There are no vaccines or antiviral therapies for Chikungunya virus. The longer-term goal of our research is to provide greater understanding of the virus replication cycle - in order to develop attenuated vaccines and novel antiviral targets. As part of the Tuplin group you will trained within an active cross-disciplinary research environment.
4 year fully-funded programme of integrated research and skills training, starting Oct 2020:
• Research Council Stipend
• UK/EU Tuition Fees
• Conference and research funding
At least a 2:1 honours degree or equivalent. We welcome students with backgrounds in biological, chemical or physical sciences, or mathematical backgrounds with an interest in biological questions.
EU candidates require 3 years of UK residency to receive full studentship
Not all projects will be funded; the DTP will appoint a limited number of candidates via a competitive process.
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