Engineering and Physical Sciences Research Council Featured PhD Programmes
European Molecular Biology Laboratory (Heidelberg) Featured PhD Programmes

Human retinal organoids as a tool for investigating mechanisms of circadian clock control


Faculty of Medicine

Saturday, October 31, 2020 Awaiting Funding Decision/Possible External Funding

About the Project

We are seeking a talented and motivated PhD student to join a research team headed by Dr. Tomas
Barta at Masaryk University, Faculty of Medicine (med.muni.cz/histology/tomas-barta/).
The successful candidate will have the opportunity to perform research in the area of molecular
mechanisms of circadian clock control and human retinal organoids derived from pluripotent stem cells.
The major research focus is on the role of light in the regulation of circadian clock core machinery.
However, contribution to other research projects that use human retinal organoids to address other
aspects of human retinal physiology is also anticipated. The selected candidate will have access to stateof-
the-art methodology and instrumentation (live imaging, lentiviral gene delivery, gene editing, highresolution
confocal microscopy, NGS, pluripotent stem cells, organoids).
We offer:
· to gain experience in tissue culture of human pluripotent stem cells and organoid generation
· to learn new methods
· friendly environment of young enthusiastic group with international collaborations
· to gain experience in grant proposal and manuscript writing
· 0.4 FTE salary + stipend
We require:
· MSc in molecular or cell biology/genetics/biochemistry or in another relevant field
· familiar with basic molecular, cell, and biochemical methods
· interest to learn new methods
· able to work independently
· critical thinking
How to apply?
Send a cv and a brief letter of interest to Tomáš Bárta ()

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