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Identification and Management of cardiovascular risk factors during and after pregnancy


   School of Nursing and Midwifery

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  Prof D Fitzsimons, Dr Fionnuala Mone, Dr J McNeill  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

About the Project: There is significant potential for women with cardiac risk factors or disease during pregnancy to experience future adverse cardiovascular events.  Cardiac disease may be related to pregnancy as a direct or indirect cause and contributes to maternal morbidity and mortality. Emerging evidence has highlighted the potential risk of pregnancy-related adverse events occurring later in life, however data are limited. In addition, the increasing number of women with congenital heart disease experiencing pregnancy has highlighted the importance of cardiovascular risk identification and management during and after pregnancy. Thus, there is a need to better understand the relationship between cardiovascular risk factors identified during pregnancy and future health outcomes, as well as to explore women’s experience of and preferences for cardiovascular risk management during and after pregnancy.

Aim: This project will aim to investigate the relationship between cardiovascular risk factors identified during pregnancy and future cardiovascular outcomes and explore women’s experience of and preferences for cardiovascular risk management during and after pregnancy.

Method: The study will take a mixed methods approach to address this aim and firstly, identify a cohort of women with cardiac disease and follow up pregnancy outcome and long-term maternal cardiovascular outcomes over a 20+ year period using data capture from routine electronic systems used within maternity services such as the Northern Ireland Maternity Information System (NIMATS). It is anticipated the study will utilise a matched cohort design to compare outcomes for women with and without heart disease. Subsequently the study will identify a contemporary sample of pregnant women with cardiovascular risk factors or disease and use interviews to explore their experience of cardiovascular risk identification and management, articulating their preferences for future cardiovascular disease prevention strategies.

Results & Impact: The findings of this study will draw much needed attention to maternal cardiovascular risk in Northern Ireland. This will help to inform the development of a more cohesive prevention strategy underpinned by analysis of population level data integrated with the perspectives of women impacted by cardiovascular risk or disease.

For further information please contact Dr Jenny McNeill, School of Nursing & Midwifery, QUB by email: [Email Address Removed]


Funding Notes

Funded by the Department for the Economy (DfE). To be considered eligible candidates must have been ordinarily resident in the UK for the full 3 year period prior to the start of the studentship and you must be ordinarily resident in Northern Ireland on the first day of the start of the studentship. For further information about eligibility criteria please refer to the DfE Postgraduate Studentship Terms and Conditions Full eligibility criteria: https://www.economy-ni.gov.uk/sites/default/files/publications/economy/Postgraduate-studentships-terms-and-conditions.pdf

References

Hauspurg A, Ying W, Hubel CA et al 2018 Adverse pregnancy outcomes and future maternal cardiovasular disease. Clin Cardiology 41;2, 239-246
Siu SC, Lee DS, Rashid M et al 2021 Long-term cardiovascular outcomes after pregnancy in women with heart disease. JAMA 10;11, doi.org/10.1161/JAHA.120.020548
Wang MC, Freaney PM, Perak AM et al 2021 Association of pre-pregnancy cardiovascular risk factor burden with adverse maternal and offspring outcomes. Eur Jour Prevent Cardiology doi:10.1093/eurjpc/zwab121
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