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Identifying acute stroke triggers


   Menzies Institute for Medical Research

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  Assoc Prof Seana Gall  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

About the research project - https://www.utas.edu.au/our-research/research-degrees/available-projects/health-and-medicine/area/menzies-institute-of-medical-research/identifying-acute-stroke-triggers

When Mrs Smith presents to hospital following her ischaemic stroke, we can tell her that her high BP, obesity, and history of smoking contributed to her stroke, but we cannot answer the question of ‘Why did this happen to me now?’. When talking to a person who has had a stroke, he or she will offer explanations for why it happened on that Tuesday, at that time, with common responses including that they were doing something strenuous or were feeling very stressed. There is reasonable evidence from small studies of varying quality that acute alcohol abuse and infection are acute risk factors of stroke, but the scientific reality is that we do not understand the acute triggers of stroke very well. This project aims to identify these acute risk factors to improve management and reduce the incidence of stroke.

The project will use a large, linked dataset including around 500,000 Tasmanians that used a pathology service between 2004 and 2020. Linkage to emergency department presentations, hospital admissions and deaths will be used to identify incident strokes during the time period. Comparison non-stroke incident events will also be identified such as for cardiac or respiratory diseases. The project will use statistical modelling working with big data to identify novel risk factors including health service contacts (e.g. hospitalisation presentations, pathology, antenatal services) among people later presenting with stroke compared to other non-stroke conditions.

This research will identify risk factors for acute stroke to inform a range of interventions, such as targeted GP referrals for people who are identified as being at high risk of stroke prior to discharge for a non-stroke admission. This PhD project is part of the Synergies to Prevent Stroke (STOPstroke) NHMRC Synergy Grant program, contributing to theme 1 around ‘Better prediction of those that will suffer stroke’.

Funding

Applicants will be considered for a Research Training Program (RTP) scholarship or Tasmania Graduate Research Scholarship (TGRS) which, if successful, provides:

  • a living allowance stipend of $28,597 per annum (2021 rate, indexed annually) for 3.5 years
  • a relocation allowance of up to $2,000
  • a tuition fees offset covering the cost of tuition fees for up to four years (domestic applicants only)

If successful, international applicants will receive a University of Tasmania Fees Offset for up to four years.

As part of the application process you may indicate if you do not wish to be considered for scholarship funding.

Eligibility

The project is open to domestic (Australian and New Zealand) and international applicants.

Applicants should review the Higher Degree by Research minimum entry requirements.

Selection Criteria

The project is competitively assessed and awarded.  Selection is based on academic merit and suitability to the project as determined by the College.

Additional desirable selection criteria specific to this project:

  • Experience with statistical analysis
  • Experience with large datasets

Application process

After checking and ensuring that you meet the eligibility and selection criteria contact the project supervisor.

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