We are seeking talented, motivated students with a passion for research in cardiovascular immunology, chronic inflammatory diseases (e.g., Atherosclerosis, psoriasis, other diseases with a chronic inflammatory component) drug discovery/ development of novel therapeutics, to join the Cardiovascular Immunology group led by Prof Ed Rainger. Applicants should have a first or upper second-class degree in a relevant scientific discipline, and who are self-funded or have typically applied for, or secured funding for their studies from their government, employer or associated charitable organisations.
RESEARCH IN THE CARDIOVASCULAR IMMUNOLOGY TEAM
The Cardiovascular Immunology team is part of the wider Leukocyte Trafficking Group in the Institute of Cardiovascular Sciences at the University of Birmingham. We are interested in identifying new pathways that control inflammation that can lead to the development of novel anti-inflammatory medicines for chronic inflammatory, auto-immune and immune mediated inflammatory diseases. These need not be restricted to the cardiovascular system.
We have three main areas of interest:
• How inflammation in the artery wall leads to atherosclerosis
• How inflammation is regulated by the PEPITEM pathway in numerous tissues and disease states
• Developing new anti-inflammatory drugs from the PEPITEM pathway which may be beneficial across a range of immune mediated inflammatory disease.
• We have ongoing projects examining:
• The role of macrophages and foam cells in atherosclerosis
• the ability of PEPITEM and its peptide mimetics to regulate inflammation
• Developing new drugs from PEPITEM and understanding there activity in immune mediated inflammatory diseases.
We have a broad portfolio of technical expertise, ranging from in vitro models of leukocyte trafficking, more complex organ on a chip models of different disease environments, links to clinical collaborators for ex vivo studies in patients with inflammatory disease and preclinical (animal) models of acute or persistent inflammation and disease.
PhD projects, using these approaches, answering translationally relevant research questions are available to self-funded or scholarship-funded graduates interested in joining The Cardiovascular Immunology Team.
APPLICATION ROUTES
Self-funded or scholarship-funded graduates interested in joining the team can select one of 3 different routes for undertaking a PhD in the field of Cardiovascular Sciences.
Applicants with research experience and/or Master’s degree should apply directly to the Institute of Cardiovascular Sciences for either a 3 or 4 year full-time PhD – https://www.birmingham.ac.uk/postgraduate/courses/research/med/cardiovascular-sciences.aspx This route requires applicants to submit a drafted research proposal.
Applicants seeking additional research experience or who have yet to complete a Master’s degree should apply to the 4 year Integrated Doctoral Training Programme in Life Sciences for Health, which combined a MRes and PhD – https://www.birmingham.ac.uk/postgraduate/pgr/idtp/index.aspx.
Applicants will need to submit the following documentation during the application process.
• Detailed CV, including your nationality and country of birth;
• Covering letter highlighting your research experience/capabilities and why you wish to undertake a PhD in the team;
• Names and addresses of two referees;
• Copies of your degree certificates with transcripts written in English;
• Evidence of your proficiency in the English language, if applicable.
• Evidence of scholarship application/funding or independent funding.
ADDITIONAL INFORMATION
University of Birmingham offers pre-sessional English Language courses through the Birmingham International Academy – https://www.birmingham.ac.uk/international/bia/presessional/index.aspx
For additional information on postgraduate studying at University of Birmingham please click - https://www.birmingham.ac.uk/study/postgraduate
For additional information on research at the College of Medical and Dental Sciences please click – https://www.birmingham.ac.uk/research/activity/mds/index.aspx
For additional information on research in the Institute of Cardiovascular Sciences please click – https://www.birmingham.ac.uk/research/cardiovascular-sciences/index.aspx
Continue with Facebook