Corticosteroid stress hormones are released throughout the day in hourly pulses with a peak in secretion prior to the onset of the active period (early morning for humans, early evening for rodents). This secretion pattern is controlled by corticotropin-releasing hormone (CRH) neurons in the brain and corticotroph cells in the pituitary. This PhD project will use calcium imaging in CRH neurons and corticotroph cells both in vitro and in vivo to understand how these daily rhythms of stress hormone secretion are generated.
Applications to undertake a PhD in Physiology are welcome at any time. Candidates can be of any nationality and must have attained an excellent degree (MSc with significant research component or a 4 years of Bachelors with Honours degree) in biomedical science or a closely-related subject.
1. Applicants are encouraged to first contact the supervisor(s) by email with the following details: o Your name and country of citizenship o Your CV o Certified academic transcript (and, if applicable, an explanation of the content) o Certified evidence of English language proficiency (eg IELTS or TOEFL results) o The names of two referees 2. If your application is to be considered, the supervisor will contact you to discuss the next steps, and our Departmental Administrator will check that your documents are complete. 3. Funding: The PhD project will be funded by the University of Otago doctoral scholarship (tuition fees and a tax-free personal allowance of NZD$27,000 pa for 36 month). Successful candidates are expected to apply and be awarded a scholarship.