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Improving the efficacy and delivery of the treatment of neurodegenerative disorders

  • Full or part time
    Dr P Rendle
  • Application Deadline
    Applications accepted all year round
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

A PhD scholarship is available for an international or New Zealand candidates to work on the design and synthesis of molecules to treat neurological diseases. Dr Rendle’s team at the Ferrier Research Institute have been working on potential treatments of a class of genetically inherited neurodegenerative diseases. This involves the synthesis of molecules to interfere with the abnormal interaction of specific proteins. This PhD project will take our current leads and improve on their efficacy and delivery. It will involve the design and multi-step chemical synthesis of targets using techniques such as anhydrous reaction conditions, column chromatography, NMR, MS and HPLC. Some practical experience of multi-step organic synthesis in a laboratory and an appreciation of good practice health and safety and record keeping are essential. The candidate will receive full training and guidance through all aspects of the project. The compounds synthesised will be evaluated biologically by collaborators.

The work will be based at the Ferrier Research Institute at Victoria University of Wellington, Wellington, New Zealand (www.victoria.ac.nz/ferrier), supervised by Dr Phillip Rendle (www.victoria.ac.nz/ferrier/about/staff/phillip-rendle).

The candidate will hold a BSc (Hons) or MSc in organic or medicinal chemistry, synthetic drug discovery or a related discipline with significant practical organic chemistry experience, and will be enthusiastic and passionate about research.

To apply: Please contact Dr Rendle (via ) to explain your interest in this project and how this relates to your previous experience. Please include a copy of your CV, academic transcript, and the names of three referees.

Funding Notes

The applicant must be eligible for admission to the PhD programme at Victoria University of Wellington. A GPA of 7.5 or greater (on a 9 point scale), a Honours or Masters degree and demonstration of proficiency in English are essential. The PhD scholarship provides for tuition fees, student levies and a tax-free personal allowance of NZ$27,500 per annum for three years. International candidates receive the same package as New Zealand residents provided they reside in New Zealand for the duration of the project and study under a New Zealand student visa.

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