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In vitro synthetic biology: surface modified molecular machines

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  • Full or part time
    Dr M Dymond
    Dr P Cragg
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

Are you interested in working at the forefront of biotechnology? Do you want to develop independent research skills? A PhD studentship is offered in the general area of in vitro synthetic biology; working on a project developing novel methods for the rapid prototyping of biodevices.

The successful applicant will initially develop methodology for the efficient tethering of bioactive molecules in precise locations on surfaces. The potential of ‘click chemistry’ will be investigated alongside other chemical linker technologies .Typically the molecules to be used are DNA, lipids and proteins however there is flexibility in the project to also explore tethering modified bacteria and supported bilayers.

As the project progresses it will move to an applications and testing phase, where proof-of-concept studies will be explored. Initially these will focus on the production of functional RNAs and proteins within biodevices but ultimately tackles the challenge of synthesising simple biological molecules from tethered protein networks.

The PhD student will be jointly supervised by Dr Marcus Dymond and Dr Peter Cragg from the School of Pharmacy and Biomolecular Sciences, University of Brighton. The successful candidate will receive cross disciplinary training in aspects of molecular biology, synthetic chemistry and bioengineering.

The successful applicant will be expected to have a Bachelor’s Honours degree in Chemistry or a related subject, awarded with first or upper second-class or an equivalent qualification.

Funding Notes

Open to UK/EU students this studentship covers annual tuition fees and a contribution towards living expenses of £14,300 per year for 3 years. A consumables fund of £2,000 p.a. is included in the award. This PhD studentship is funded by the School of Pharmacy and Biomolecular Sciences, University of Brighton. This would be for a January2015 entry.

Administrator to the project, Alice Parkes [Email Address Removed] +44 01273 641104



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