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Individual biomarkers of iodine status – from population studies to personalised assessment


Research

Monday, September 21, 2020 Competition Funded PhD Project (Students Worldwide)

About the Project

Applications are invited for an ITSligo President’s Bursary 2020

PROJECT TITLE: Individual biomarkers of iodine status – from population studies to personalised assessment

FUNDING SOURCE: President’s Bursary 2020 with a maintenance grant of €13,000 p.a. and upto €4,000 p.a. for expenses as approved. Tuition fees (currently €819 p.a.) will be paid by the Institute for all holders of student bursaries. Students are required to pay their registration fee. The registration fee for 2020-2021 is €3,000 p.a.

DURATION: Funding will be initially for a maximum of 2 years full time Master’s registration. This research has the potential to transition into a PhD up to a maximum of 4 years.

Description: Iodine deficiency, especially in pregnant women, still remains a common global problem. However, there is a lack of relevant individual biomarkers of iodine status. The aim of the project is to identify novel biomarkers of individual iodine status in humans to improve the personalized assessment of iodine nutritional status, which is currently impossible. The hypothesis of the project is that iodine concentration in saliva is an adequate and reliable individual biomarker of iodine status due to iodide secretion into saliva via sodium-iodide synporters expressed in the salivary glands.
The following tasks should be solved to achieve the aim:
• Design an analytical method to quantify iodine in saliva.
• Ensure the validity of the method and assess its analytical figures of merit.
• Test the method as a potential biomarker.
• Test the novel biomarker in a wider cohort to compare and evaluate it within the context of existing iodine biomarker data.

Profile Requirements
Motivated candidates with strong interests in analytical chemistry, epidemiology and statistics are encouraged to apply. Candidates must have an Honours Degree in relevant discipline including Analytical Chemistry and/or Forensics, Pharmaceutical Sciences or Human Nutrition (essential). Candidates with substantial expertise in inorganic analysis or bioanalytical chemistry will be considered favourably. ITSligo welcomes applications from eligible International candidates.

To Apply
Please send by email to Dr Nikolay Solovyev, () and CC Veronica Cawley (
1) A detailed cover letter
2) A full curriculum vitae
3) Academic transcripts for each year of study
4) Contact details of two academic referees

Applicants whose first language is not English must submit the original certificate of completion of an English test.

Please insert the subject line ‘IT Sligo President’s Bursary 2020’ with your electronic correspondence.

Closing Date for Applications: 17:00 local time, 21st of September 2020


Funding Notes

See Above

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