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Infralucifern/luciferase gold nanorod conjugates for NIR bi-modal imaging

  • Full or part time
  • Application Deadline
    Thursday, April 30, 2020
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

UCL Chemistry Department is offering a fully funded studentship to a highly motivated candidate to start in September 2020. The project will be in collaboration with Prof A. Tabor (Chemistry) and Dr T. Kalber (UCL Centre for Advanced Biomedical Imaging). The student will carry out his/her doctoral research at UCL.

The project will synthesise infraluciferin derivatives linked to an active linker (Anderson lab) for coupling to an active linker on gold nano particles (Tabor lab) for assessing particle cell internalisation and delivery (Kalber lab). Particle location will be assessed by high resolution photoacoustic imaging. Whereas, infraluciferin will verify cell internalisation by activating bioluminescence. The student will get a training in modern organic synthesis, techniques in bio-conjugation and experience of biomedical imaging. For a more comprehensive description contact Prof. Jim Anderson ()

The applicants should have, or be expecting to achieve, a first or upper second class Honours degree or equivalent in Chemistry.
Interested candidates should initially contact the supervisor Prof. Jim Anderson () with a CV including the names and contact details of 2 referees, degree transcript and a motivation letter expressing interest in this project. Informal inquiries are encouraged. Suitable candidates will be required to complete an electronic application form at http://www.ucl.ac.uk/prospective-students/graduate/apply. Shortlisted applicants will be expected to undergo an interview for the position. Any admissions queries should be directed to Dr Jadranka Butorac ().

Applications will be accepted until 30 April 2020, but the position will be filled as soon as a suitable candidate has been identified.


Funding Notes

Due to funding restrictions, this studentship is only open to applicants from the UK and EU, who have been resident in the UK for at least 3 years preceding their start on the programme or have indefinite leave to remain in the UK.

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