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Innovative bioseparation resins

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

The manufacture of biopharmaceuticals, such as therapeutic proteins, is increasingly facing limitations due to insufficient performance of existing purification processes. There is an urgent need for new bioseparation resins and methods to overcome this biomanufacturing bottleneck. This project aims to develop an innovative and disruptive platform technology for designing and manufacturing tailor-made high-performance bioseparation resins, to enhance manufacturing of biopharmaceuticals. Bacterial cell factories will be designed to produce polymer spheres which densely display specific binding domains for purification of biopharmaceuticals.

Funding Notes

About the Scholarship

The 2019 Griffith University Postgraduate Research Scholarship has an annual stipend of $27,596 (indexed) for a period of up to three years of full-time study. Please see the GUPRS Conditions of Award for more information: View Website

A successful International applicant will also be awarded a Griffith University International Postgraduate Research Scholarship to cover tuition fees for up to three years. Please see the GUIPRS Conditions of Award for more information: View Website

References

1. Rehm, B. H. A. et al., Self-Assembled Protein-Coated Polyhydroxyalkanoate Beads: Properties and Biomedical Applications. ACS Biomaterials Science & Engineering 2017, 3 (12), 3043-3057.

2. Du, J.; Rehm, B. H. A., Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions. Microbial Cell Factories 2017, 16 (1), 184.

3. Du, J.; Rehm, B. H. A., Purification of therapeutic proteins mediated by in vivo polyester immobilized sortase. Biotechnology Letters 2018, 40 (2), 369-373.

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