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Innovative statistical methods for clinical trial pathways supporting regulatory drug approval

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  • Full or part time
    Prof N Stallard
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

PhD in Interdisciplinary Biomedical Research

Fully funded studentship available for entry in September 2019

This Industrial Collaborative Award in Science and Engineering (iCASE) studentship is offered by Warwick’s MRC Funded Doctoral Training Partnership (DTP). This training program involves an exciting one-year MSc in Interdisciplinary Biomedical Research and then a three-year PhD project which is co-supervised by experts from both academia and industry. The student will benefit from a comprehensive training program that offers advanced workshops, career planning, transferable skills training and cohort learning events and conferences with ~ 50 other PhD students.

Title: Innovative statistical methods for clinical trial pathways supporting regulatory drug approval

University of Warwick and Industry Supervisors: Prof. Nigel Stallard (University of Warwick) and Dr Cornelia Ursula Kunz (Boehringer Ingelheim)

Project summary

In collaboration with Boehringer Ingelheim, this PhD project will address important questions in the statistical design of clinical trials conducted to support the regulatory approval of new drugs. The project will involve modelling of decision-making and optimal design approaches for clinical trials, including the use of flexible innovative trial designs and the incorporation of external historical or concurrent data in the evidence base used to support regulatory approval. Statistical techniques involved will include the control of frequentist error rates, Bayesian and decision-modelling methods.

Applicants should have a good undergraduate degree in statistics or a related discipline.

Warwick’s MRC DTP Overview

MSc Course (Year One)
A one-year taught MSc in Interdisciplinary Biomedical Research, including taught modules (e.g. frontier techniques and research skills in biomedicine, principles and techniques in molecular biology, advanced microscopy and imaging, molecular modelling and physical biology of the cell) and two 11-week research projects.

PhD Project (Years Two – Four)
A three-year PhD project. Students will be supervised jointly by a Warwick Principal Investigator and an industry partner, and will undertake a minimum of three months’ placement with the industry partner.

If you are interested in joining our dynamic DTP community please apply at www.warwick.ac.uk/fac/sci/med/study/mrcdtp/theprogramme/icase/ by Thursday 14 February 2019.

Interviews will take place on Monday 8 April 2019.

Funding Notes

Funding
Studentships covering full fees, consumables and annual stipend of £17,499 * are available. https://warwick.ac.uk/fac/sci/med/study/mrcdtp/apply/funding/ for full information.

Entry Requirements
A strong first degree (2i or above) or international equivalent in a relevant subject. Please see the website for further information about academic entry and residency requirements.

* to be confirmed.



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