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Integrating molecular self-assembly with additive manufacturing for biomedical applications.

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  • Full or part time
    Prof R Wildman
    Prof A Mata
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Nature has evolved to grow and regenerate tissues and organs using self-assembling processes capable of organizing a wide variety of molecular building-blocks at multiple size scales. As the field of biofabrication progresses, it is essential to develop innovative ways that can enhance our capacity to build more complex macroscopic structures using molecular and nanoscale components organized across size scales and in a rational manner. In this context, unifying additive manufacturing with molecular self-assembly represents a new approach to biofabrication with the potential to create structures with an unprecedented level of hierarchy, complexity, and functionality.

The project will be led by Profs. Ricky Wildman and Alvaro Mata and will optimize new self-assembling bioinks from the Mata Group and incorporate them with innovative additive manufacturing processes developed in the Centre for Additive Manufacturing. The bioinks comprise components such as peptides, proteins, and graphene and are designed to self-assemble into well-defined nano- and micro-structures that can selectively stimulate cells. The work will bridge between additive manufacturing where there is a need to optimise process and material design for biological use and self-assembling materials where we look to exploit supramolecular phenomena such as compartmentalization, diffusion-reaction processes, and protein order-disorder transitions.

We seek candidates with an interest in the development of biomaterials based around hydrogels, supramolecular chemistry and biomolecules for use within 3D printing systems.

The successful candidate will receive a full studentship (fees and stipend at UK/EU rates only) for 3 years.

Funding Notes

Eligibility
Applicants should have, or expect to obtain, a 1st class or 2:1 degree in Engineering, Physics, Chemistry or Science related discipline.

How to apply
Please send your covering letter, CV and academic transcripts to [Email Address Removed] referring to the project title. Please note applications without academic transcripts will not be considered.

Start date: The studentship is available to start immediately, no later than October 2020.

Deadline: 23rd March 2020.
Please note that the position will be filled as soon as a suitable person has been found, therefore you are encouraged to apply as soon as possible.



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