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  Intestinal Microbiome Modulation using Next Generation Probiotics


   College of Medical and Dental Sciences

  ,  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

We are seeking talented, motivated students with a passion for research in microbiology, gastrointestinal health and probiotic delivery led by Dr Richard Horniblow (Associate Professor in Gastrointestinal Biomedical Science) at the College of Medical and Dental Sciences and the University of Birmingham (https://www.birmingham.ac.uk/staff/profiles/clinical-sciences/horniblow-richard.aspx). Applicants should have a first or upper second-class degree in a relevant scientific discipline, and who are self-funded or have typically applied for, or secured funding for their studies from their government, employer or associated charitable organisations.

How does the intestinal microbiome influence disease and can we target it as a treatment strategy?

Research within the group focusses on how the intestinal microbiome influences health and well-being. Using data generated from our ongoing Faecal Microbial Transplantation studies (in collaboration with Prof Iqbal at the Queen Elizabeth Hospital Birmingham), we are identifying bacterial bio-actives that may have utility as a therapy by altering the composition of the intestinal microbiome when successfully delivered as a probiotic. As such, we are interested in understanding how such probiotic treatments could be useful in a clinical setting and understanding the molecular mechanisms behind their action. We combine a range of cross-discipline technologies and methods to enable us to understand this, from anaerobic microbiology, probiotic drug development and sequencing. PhD projects, using these approaches, answering clinically relevant research questions are available to self-funded or scholarship-funded graduates.

How to apply

Applicants are invited from self-funded or scholarship-funded graduates only.

Informal enquiries should be directed to Dr Richard Horniblow ().

Applicants will be self-funded or will have typically applied for, or secured funding for their studies from their government, employer or associated charitable organisations.

Applicants should apply directly to the School of Biomedical Sciences (using this link: https://www.birmingham.ac.uk/postgraduate/courses/research/med/biomedical-sciences.aspx). This route requires applicants to submit a drafted research proposal which can be co-curated with Dr Richard Horniblow.

Applicants will need to submit the following documentation during the application process.

• Detailed CV, including your nationality and country of birth;

• Covering letter highlighting your research experience/capabilities and why you wish to undertake a PhD in the team;

• Names and addresses of two referees;

• Copies of your degree certificates with transcripts written in English;

• Evidence of your proficiency in the English language, if applicable.

• Evidence of scholarship application/funding or independent funding.

Additional Information:

University of Birmingham offers pre-sessional English Language courses through the Birmingham International Academy.

For additional information on postgraduate studying at University of Birmingham please click - https://www.birmingham.ac.uk/study/postgraduate

For additional information on research at the College of Medical and Dental Sciences please click – https://www.birmingham.ac.uk/research/activity/mds/index.aspx

Biological Sciences (4) Food Sciences (15) Medicine (26)

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