or
Looking to list your PhD opportunities? Log in here.
Brain tumours are highly invasive and carry a poor prognosis. Secondary brain tumours or brain metastases (BM) are the most common tumours found in the brain affecting up to one third of patients with solid organ cancer. Brain tumours are treated with a combination of surgery, radiotherapy and systemically administered drugs, including in some cases immunotherapy.
Our research group which encompasses neurosurgery, veterinary surgery, neuropathology, radiology, immuno-oncology and BBB biologists is developing a number of projects examining the mechanisms of local invasion in brain tumours and the tumour/microenvironmental drivers and modulators of this process. This has implications for clinical diagnostics and therapeutics. Projects leverage the UoL Shared Research Facilities including multi-omics, spatial transcriptomics at the Centre for Genomic Research and 9T small animal MRI, PET and bioluminescent imaging at the Centre for Preclinical Imaging.
The group is translational with surgically obtained tissue driving laboratory investigations, models and hypotheses which can then be taken back to the clinic. There is a strong background of delivering pragmatic clinical trials in neuro-oncology along with the partner NHS Foundation trust, The Walton Centre which also hosts a comprehensive, ethically approved tissue bank.
Applications and enquiries directly to the main supervisor via email with CV and covering letter.
Based on your current searches we recommend the following search filters.
Check out our other PhDs in Liverpool, United Kingdom
Start a New search with our database of over 4,000 PhDs
Based on your current search criteria we thought you might be interested in these.
Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain
University of Nottingham
Understanding how to target the T cell compartment within related brain tumours
The University of Manchester
Utilising preclinical models for investigating pathological mechanisms underlying cognitive deficits in brain disorders - focus on exploring novel treatments.
The University of Manchester