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  Investigating selenium doped collagen-glycosaminoglycan scaffolds as a novel treatment for bone cancer


   Anatomy and Regenerative Medicine

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  Dr Ciara Murphy  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

The project will develop a therapeutic biomaterial platform to restore structural integrity and function in cancer-damaged bone, combining nano-therapeutics and biomaterial technologies to produce a dual function, anti-cancer and pro-regenerative scaffold for the treatment of bone defects resulting from tumour resection. This is an extremely important and timely clinical topic, which represents a significant burden to healthcare worldwide and is a considerable socio-economic problem. The project will require detailed in vitro and in vivo assessment of the platforms healing potential, which will include histological and ultrastructural analysis, combined with a molecular analysis of protein distribution and gene expression in situ. 

The successful candidate will be a part of Tissue Engineering Research Group (TERG), a multi-PI network based at RCSI. This highly dynamic research environment has over 30 early career researchers (including PhD/MSc students and Postdoctoral fellows) and the successful applicant will have a wide opportunity to interact with peers and near-peers of the various groups affiliated with TERG. Day-to-day supervision in the laboratory and safety guidance will also be supported by dedicated technical staff. 

The successful candidate will also have opportunities to be involved in and to gain hands-on experience in the teaching activities of the Department of Anatomy and Regenerative Medicine, which include macroscopic anatomy and biology.

Mandatory Specifications:

Minimum of an Upper Second-Class Honours (2.1) Bachelor’s degree, or equivalent, in Material Sciences, Mechanical Engineering, Biomedical Engineering or related disciplines. 

Excellent written and oral communication skills and a high level of competence in the English language. 

Ability to work independently, to take initiative and discuss/develop and communicate own ideas

Desirable Skills:

Experience in cell culture

Application Process/ How do I apply section  

To apply, please access the following link and complete the application form in full: https://forms.office.com/e/wxbiw0yQGz

-Unfortunately, we are unable to provide individual feedback to applicants.

-Shortlisted candidates will be invited for interview. 

-At this stage only successful candidates will be contacted to submit, CV, transcripts and other relevant documentation.

- Only their referees will also be contacted at this stage for a reference.

Applications must include:

(i) a completed application form

(ii) English language requirements – see https://www.rcsi.com/dublin/postgraduate/policies-and-guidelines/english-language-requirements.

Deadline: All applications must be made online by 30th June 2023

It is the candidate’s responsibility to ensure the application form is completed in full on time. Late and/or incomplete applications will not normally be assessed. 

Biological Sciences (4) Medicine (26)
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 About the Project