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Investigating the molecular basis of this adhesion and the development of tetraspanin-based reagents for preventing bacterial infections


Department of Molecular Biology and Biotechnology

Dr L J Partridge Applications accepted all year round Self-Funded PhD Students Only

About the Project

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM). We have recently found that a number of bacterial species appear to “hijack” TEM as a means of adhering to and infecting mammalian cells. The project will investigate the molecular basis of this adhesion and the development of tetraspanin-based reagents for preventing bacterial infections.


Science Graduate School

As a PhD student in one of the science departments at the University of Sheffield, you’ll be part of the Science Graduate School – a community of postgraduate researchers working across biology, chemistry, physics, mathematics and psychology. You’ll get access to training opportunities designed to support your career development by helping you gain professional skills that are essential in all areas of science. You’ll be able to learn how to recognise good research and research behaviour, improve your communication abilities and experience technologies that are used in academia, industry and many related careers. Visit http://www.sheffield.ac.uk/sgs to learn more.

Funding Notes

Entry requirements
First class or upper second 2(i) in a relevant subject. To formally apply for a PhD position, you must complete the University's application form using the following link: View Website

*All applicants should ensure that both references are uploaded onto their application as a decision will be unable to be made without this information*.





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