Investigating the nanophysical properties of biomolecular structures

The aim of this highly interdisciplinary project is to explore the mechanical and electrical properties of biomolecular structures such as DNA, chromosomes, protein fibers or cell membranes. The main tool to be used is Atomic Force Microscopy (AFM), with which we can determine these properties with unsurpassed sensitivity and resolution at the nanometer scale. We are particularly interested in the influence of carbohydrates on the electrostatic charge and the tensile strength of biomaterials. This has profound implications not only on fundamental biological processes such as cell adhesion but also on applications in tissue-engineering.

This project is suitable for a motivated PhD student with a background in Physics, Chemistry or Materials/Engineering. The project is conducted in close collaboration with researchers in the Life Sciences at King’s and at the Vienna University of Technology. The student must, therefore, be willing to spend a few weeks in Austria if required.

In the Experimental Biophysics and Nanotechnology Group of the Department of Physics at King’s College London, we are very well placed to offer a stimulating environment for this project. We have excellent, state-of-the-art lab facilities and all the necessary equipment, incl three high-end AFMs. The student will be embedded in a large group of PhD students with a diverse, international background in Central London. Furthermore, the College offers a huge range of seminars and transferrable-skills courses that can provide a competitive edge in today’s job market.

Applicants must hold, or expect to receive, a first or upper second class honours degree (or equivalent) in Physics, Chemistry, Mechanical or Electrical Engineering, Materials Sciences, or similar.